N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- Product Name
- N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- CAS No.
- 143722-29-6
- Chemical Name
- N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- Synonyms
- Butanoicacid,4-chloro-6-oxo-;1-(1H-1,3-BENZODIAZOL-2-YL)-1H-PYRAZOL-7-AMINE;1-(4-bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde;N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde;3-[(4-Bromophenyl)methyl]-2-butyl-5-chloroimidazole-4-carbaldehyde;1-[(4-BroMophenyl)Methyl]-2-butyl-4-chloro-1H-iMidazole-5-carboxaldehyde;1H-Imidazole-5-carboxaldehyde, 1-[(4-bromophenyl)methyl]-2-butyl-4-chloro-
- CBNumber
- CB62503134
- Molecular Formula
- C15H16BrClN2O
- Formula Weight
- 355.66
- MOL File
- 143722-29-6.mol
N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Chloroform, Dichloromethane, Ethyl Acetate, Methanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B680195
- Product name
- N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- Packaging
- 50mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FB19202
- Product name
- N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- Packaging
- 50mg
- Price
- $254.5
- Updated
- 2021/12/16
- Product number
- FB19202
- Product name
- N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- Packaging
- 100mg
- Price
- $462
- Updated
- 2021/12/16
- Product number
- 2808AQ
- Product name
- 1-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde
- Packaging
- 1g
- Price
- $622.4
- Updated
- 2021/12/16
- Product number
- FB19202
- Product name
- N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde
- Packaging
- 250mg
- Price
- $840
- Updated
- 2021/12/16
N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde Chemical Properties,Usage,Production
Uses
Intermediate in the production of Sartan derivatives
Synthesis
83857-96-9
589-15-1
143722-29-6
Example 14 Synthesis of 1-(4-bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carbaldehyde 2-n-butyl-4-chloro-1H-imidazole-5-carboxaldehyde (111.9 g, 0.6 mol), p-bromobenzyl bromide (153.02 g, 0.6 mol), anhydrous potassium carbonate (103.5 g, 0.75 mol), and dry N,N-dimethylacetamide (900 mL) were mixed and the reaction was stirred for 4 hours at room temperature. After completion of the reaction, the reaction mixture was diluted with toluene (1.2 L) and water (1.8 L) and stirring was continued for 30 min. After standing and stratifying, the organic layer was separated and washed twice with 900 mL of water. The organic layer was dried with magnesium sulfate and filtered to remove the desiccant. The filtrate was concentrated and the residue was dried by vacuum pump overnight to give 191.71 g of the target product in 89.9% yield.
References
[1] Patent: US5310928, 1994, A
[2] Patent: US5130439, 1992, A
N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
N-(4-Bromobenzyl)-2-butyl-4-chloro-1H-imidazole-5-carboxyaldehyde Suppliers
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