CMPF
- Product Name
- CMPF
- CAS No.
- 86879-39-2
- Chemical Name
- CMPF
- Synonyms
- CMPF;Furanic acid;CMPF Exclusive;Propylfuranoic acid;3-carboxy-4-methyl-5-propyl-2-furanpropionic acid;3-Carboxy-4-methyl-5-propylfuran 2-propanoic acid;3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPANOIC ACID;2-Furanpropanoic acid, 3-carboxy-4-methyl-5-propyl-;CMPF, 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid;3-[(3-Carboxy-4-methyl-5-propylfuran)-2-yl]propionic acid
- CBNumber
- CB6250601
- Molecular Formula
- C12H16O5
- Formula Weight
- 240.25
- MOL File
- 86879-39-2.mol
CMPF Property
- Melting point:
- >174°C (Subl.)
- Boiling point:
- 404.0±45.0 °C(Predicted)
- Density
- 1.236±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Very Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol
- form
- Solid
- pka
- 4.38±0.10(Predicted)
- color
- White to Pale Beige
Safety
- RTECS
- LU5240766
N-Bromosuccinimide Price
- Product number
- 90833
- Product name
- 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid
- Purity
- analytical standard
- Packaging
- 10mg
- Price
- $342
- Updated
- 2024/03/01
- Product number
- 90833
- Product name
- 3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid
- Purity
- analytical standard
- Packaging
- 50mg
- Price
- $826
- Updated
- 2024/03/01
- Product number
- 10007133
- Product name
- CMPF
- Purity
- ≥98%
- Packaging
- 500μg
- Price
- $43
- Updated
- 2024/03/01
- Product number
- 10007133
- Product name
- CMPF
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 10007133
- Product name
- CMPF
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $332
- Updated
- 2024/03/01
CMPF Chemical Properties,Usage,Production
Uses
CMPF is a drug-binding inhibitor which is also a constituent of urine. CMPF can inhibit specific T4 binding in serum by increasing the free concentration of direct competitors.
Definition
ChEBI: A furoic acid that is furan-3-carboxylic acid substituted by a methyl group at position 4, a propyl group at position 5 and a 2-carboxyethyl group at position 2. It is a potent uremic toxin that has been found to accumulate in human serum of patients with hronic kidney diseases.
General Description
3-Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), a major metabolite of furan fatty acids, is a uremic toxin (UT), excreted into the urine via organic,anion transporters under physiological conditions. It is mostly reported to be accumulated in chronic kidney disease (CKD) patients. Monitoring of CMPF may be important to predict organic anion transporting polypeptide (OATP)1B activity in CKD patients as studies have implicated a decreased trend in (OATP)1B activity in patients with this uremic toxin. It is also found to be in increased concentrations, for patients who progress from prediabetes to type 2 diabetes, patients with renal failure, polyunsaturated fatty acids with high-temperature cooking and subjects who consume fish or fish oil.