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4-Bromonaphthalene-1-carbonitrile

Product Name
4-Bromonaphthalene-1-carbonitrile
CAS No.
92616-49-4
Chemical Name
4-Bromonaphthalene-1-carbonitrile
Synonyms
4-BroMo-1-naphthonitrile;1-Bromo-4-cyanonaphthalene;4-Bromo-naphthalen-1-carbonitrile;4-Bromo-1-naphthalenecarbonitrile;4-Bromonaphthalene-1-carbonitrile;1-Naphthalenecarbonitrile, 4-bromo-;1,2,3,4,5-Cyclopentanepentayl,1-[bis(4-methoxy-3,5-dimethylphenyl)phosphino]-2-[(R)-(dimethylamino)phenylmethyl]-,ironsalt(2:7)
CBNumber
CB62506852
Molecular Formula
C11H6BrN
Formula Weight
232.08
MOL File
92616-49-4.mol
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4-Bromonaphthalene-1-carbonitrile Property

Melting point:
102-103 °C
Boiling point:
352.9±15.0 °C(Predicted)
Density 
1.57±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B686008
Product name
4-Bromonaphthalene-1-carbonitrile
Packaging
1g
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
097789
Product name
4-Bromo-1-naphthonitrile
Purity
95+%
Packaging
1g
Price
$171
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0365529
Product name
4-BROMO-1-NAPHTHONITRILE
Purity
95.00%
Packaging
5MG
Price
$499.29
Updated
2021/12/16
Matrix Scientific
Product number
097789
Product name
4-Bromo-1-naphthonitrile
Purity
95+%
Packaging
5g
Price
$504
Updated
2021/12/16
AK Scientific
Product number
V9190
Product name
4-Bromo-1-naphthonitrile
Packaging
100g
Price
$691
Updated
2021/12/16
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4-Bromonaphthalene-1-carbonitrile Chemical Properties,Usage,Production

Synthesis

664364-16-3

92616-49-4

General procedure for the synthesis of 4-bromo-1-naphthalenecarbonitrile (V) from 4-bromo-1-naphthalenecarboxaldehyde oxime (IV): 141 g of the crude product of 4-bromo-1-naphthalenecarboxaldehyde oxime (IV) was added to a 3L reaction flask with 22.6 g of copper acetate monohydrate and 1137 g of acetonitrile, heated to 79 °C and refluxed overnight. The progress of the reaction was monitored by thin layer chromatography (TLC). After completion of the reaction, it was cooled to room temperature and the acetonitrile was removed by distillation under reduced pressure. To the residue, 1500 g of water was added and extracted with 1000 g of dichloromethane. The aqueous phase was extracted twice more with 500 g of dichloromethane and all organic phases were combined. The organic phase was washed with 1500 g of saturated sodium chloride solution. A desiccant was added and stirred and dried overnight. The desiccant was removed by filtration and the filtrate was rotary evaporated at 40°C to remove the solvent. Purification by short column chromatography using dichloromethane as eluent gave 124.3 g of 4-bromo-1-naphthalenecarbonitrile (V). The overall two-step yield based on 4-bromo-1-naphthalenecarboxaldehyde was 94.7% and the purity of the product was 99.3%. Among them, the molar ratio of 4-bromo-1-naphthaldehyde (IV) to copper acetate monohydrate was 1:0.2.

References

[1] Patent: CN106366018, 2017, A. Location in patent: Paragraph 0048; 0049; 0050; 0051; 0052

4-Bromonaphthalene-1-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Bromonaphthalene-1-carbonitrile Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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Anhui Lianchuang Biological Medicine Co.,Ltd
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0551-68779238 18056025720
Email
sales3@lcywhx.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
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China
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
ProdList
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Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
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Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
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9891
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
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China
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9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
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China
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18209
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
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Synchem OHG
Tel
+49 5662 408730
Fax
+49 5662 4087320
Email
info@synchem.de
Country
Germany
ProdList
4705
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View Lastest Price from 4-Bromonaphthalene-1-carbonitrile manufacturers

Career Henan Chemical Co
Product
4-Bromonaphthalene-1-carbonitrile 92616-49-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-18
Career Henan Chemical Co
Product
4-Bromonaphthalene-1-carbonitrile
Price
US $0.10/g
Min. Order
1g
Purity
99%
Supply Ability
1g-100kg
Release date
2020-01-07

92616-49-4, 4-Bromonaphthalene-1-carbonitrileRelated Search:


  • 4-Bromonaphthalene-1-carbonitrile
  • 4-BroMo-1-naphthonitrile
  • 1-Bromo-4-cyanonaphthalene
  • 1-Naphthalenecarbonitrile, 4-bromo-
  • 1,2,3,4,5-Cyclopentanepentayl,1-[bis(4-methoxy-3,5-dimethylphenyl)phosphino]-2-[(R)-(dimethylamino)phenylmethyl]-,ironsalt(2:7)
  • 4-Bromo-1-naphthalenecarbonitrile
  • 4-Bromo-naphthalen-1-carbonitrile
  • 92616-49-4