3-(benzyloxy)-4H-pyran-4-one
- Product Name
- 3-(benzyloxy)-4H-pyran-4-one
- CAS No.
- 61049-67-0
- Chemical Name
- 3-(benzyloxy)-4H-pyran-4-one
- Synonyms
- 3-(benzyloxy)-4H-pyran-4-one;4H-Pyran-4-one, 3-(phenylmethoxy)-
- CBNumber
- CB62517948
- Molecular Formula
- C12H10O3
- Formula Weight
- 202.21
- MOL File
- 61049-67-0.mol
3-(benzyloxy)-4H-pyran-4-one Property
- storage temp.
- Sealed in dry,Room Temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B593630
- Product name
- 3-(Benzyloxy)-4H-pyran-4-one
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 9136AB
- Product name
- 3-(Benzyloxy)-4H-pyran-4-one
- Packaging
- 250mg
- Price
- $128
- Updated
- 2021/12/16
- Product number
- FB141425
- Product name
- 3-(Benzyloxy)-4H-pyran-4-one
- Packaging
- 500mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FB141425
- Product name
- 3-(Benzyloxy)-4H-pyran-4-one
- Packaging
- 1g
- Price
- $281.25
- Updated
- 2021/12/16
- Product number
- 9136AB
- Product name
- 3-(Benzyloxy)-4H-pyran-4-one
- Packaging
- 5g
- Price
- $890
- Updated
- 2021/12/16
3-(benzyloxy)-4H-pyran-4-one Chemical Properties,Usage,Production
Synthesis
1219-33-6
61049-67-0
General procedure for the synthesis of 3-(benzyloxy)-4H-pyran-4-one from 5-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid: 5-benzyloxy-4-oxo-4H-pyran-2-carboxylic acid (13b) (15.87 g, 64.5 mmol) was mixed with 1-methyl-2-pyrrolidinone (160 mL) and heated and refluxed for 4 hours. After completion of the reaction, the solvent was removed by azeotropy with N,N-dimethylformamide (160 mL) under high vacuum. The residue was dissolved in dichloromethane and washed with 5% aqueous sodium hydroxide (3 x 90 mL). The organic layer was dried over anhydrous sodium sulfate, concentrated, and recrystallized from toluene to give the light yellow solid product 3-(benzyloxy)-4H-pyran-4-one (14b) (9.07 g, 70% yield).
References
[1] European Journal of Medicinal Chemistry, 2016, vol. 115, p. 132 - 140
[2] European Journal of Medicinal Chemistry, 1994, vol. 29, # 11, p. 893 - 897
[3] Farmaco, 2001, vol. 56, # 4, p. 251 - 256
[4] Journal of Medicinal Chemistry, 1996, vol. 39, # 19, p. 3659 - 3670
[5] Patent: WO2011/109254, 2011, A1. Location in patent: Page/Page column 128
3-(benzyloxy)-4H-pyran-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
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