ChemicalBook > CAS DataBase List > (+)-Piresil-4-O-beta-D-glucopyraside

(+)-Piresil-4-O-beta-D-glucopyraside

Product Name
(+)-Piresil-4-O-beta-D-glucopyraside
CAS No.
69251-96-3
Chemical Name
(+)-Piresil-4-O-beta-D-glucopyraside
Synonyms
(+)-pinor;Pinoresinol 4-glucoside;Pinoresinol 4-O-glucoside;Pinoresinol 4-glucoside-RM;(+)-pinoresinol-β-D-glucoside;Terpineol-4-o- β- D-glucoside;(+)-pinoresinol-b-D-glucoside;PINORESINOL 4-O-GLUCOSIDE 98%;(+)-pinoresinol-β-D-glucoside;(+)-Piresil-4-O-β-D-glucopyraside
CBNumber
CB62519179
Molecular Formula
C26H32O11
Formula Weight
520.53
MOL File
69251-96-3.mol
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(+)-Piresil-4-O-beta-D-glucopyraside Property

Melting point:
102-104 °C(Solv: methanol (67-56-1))
Boiling point:
752.5±60.0 °C(Predicted)
Density 
1.418±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
Solid
pka
9.84±0.35(Predicted)
color 
White to light yellow
InChIKey
QLJNETOQFQXTLI-DUAOPOKGNA-N
SMILES
O(C1=C(C=CC([C@H]2OC[C@]3([H])[C@@H](C4C=CC(O)=C(OC)C=4)OC[C@]23[H])=C1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C |&1:6,9,11,23,27,28,29,31,33,r|
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL84251
Product name
Pinoresinol 4-glucoside
Purity
phyproof<SUP>&#174;</SUP> Reference Substance
Packaging
10 mg
Price
$408
Updated
2025/07/31
Usbiological
Product number
300794
Product name
Pinoresinol 4-O-glucoside
Packaging
20mg
Price
$722
Updated
2021/12/16
ApexBio Technology
Product number
N2022
Product name
(+)-Piresil-4-O-beta-D-glucopyraside
Packaging
20mg
Price
$500
Updated
2021/12/16
Arctom
Product number
AS111007
Product name
(+)-pinoresinol-β-D-glucoside
Purity
97%
Packaging
5mg
Price
$101
Updated
2021/12/16
AvaChem
Product number
2972
Product name
Pinoresinol-beta-D-glucoside
Packaging
5mg
Price
$145
Updated
2021/12/16
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(+)-Piresil-4-O-beta-D-glucopyraside Chemical Properties,Usage,Production

Chemical Properties

Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Forsythia.

Uses

(+)-Piresil-4-O-beta-D-glucopyraside is used for content determination/identification/pharmacological experiments, etc.

Definition

ChEBI: (+)-Pinoresinol 4-O-glucoside is a lignan and a glycoside.

Biological Activity

Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the main active furofuranoside lignan in Forsythia. It has antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects.

in vivo

Pinoresinol 4-O-β-D-glucopyranoside (50 mg/kg; p.o.; 20 days for hepatoprotective activity test, 10 days for antihyperglycaemic activity test) exhibits hepatoprotective activity by lowering AST and ALT levels in CCl4 (HY-Y0298)-induced hepatotoxicity mice, and shows antihyperglycaemic activity by causing a prominent decline in serum glucose level and a promising elevation in insulin level in Streptozotocin (HY-13753)-treated mice[4].
Pinoresinol 4-O-β-D-glucopyranoside (25-50 mg/kg; p.o.; twice with the second dose 1 h before pilocarpine injection) ameliorates the seizures in a dose-dependent manner in lithium/Pilocarpine (HY-B0726A)-induced epileptic seizures rats, manifested by retarding seizure onset, reducing the number of rats developing seizures, and enhancing the survival of animals after seizure exposure[7].

Animal Model:Male Swiss albino mice (weight: 27-30 g), CCl4-induced hepatotoxicity model and Streptozotocin-induced hyperglycaemia model[4]
Dosage:50 mg/kg b.w.
Administration:Oral gavage (p.o.), 20 days in the hepatotoxicity experiment; 10 days in the hyperglycaemia experiment
Result:Led to a 33.94% decline in AST, a 3.01% decline in ALT, and a 49.96% decline in LPO levels (in the CCl4-induced hepatotoxicity model).
Significantly enhanced CAT, SOD, and TAS levels by 130%, 90.45%, and 61.39% respectively compared to the CCl4-treated group (in the CCl4-induced hepatotoxicity model).
Caused a 37.83% reduction in serum glucose level and a 25.37% increase in insulin level (in the Streptozotocin-induced hyperglycaemia model).
Reduced lipid peroxide levels by 51.77% and increased serum levels of CAT, SOD, and TAS by 93.02%, 70.79%, and 101.90%, respectively (in the Streptozotocin-induced hyperglycaemia model).

(+)-Piresil-4-O-beta-D-glucopyraside Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Piresil-4-O-beta-D-glucopyraside Suppliers

cjbscvictory
Tel
13348960310
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3003867561@qq.com
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China
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Chengdu RefMedic Biotech Co Ltd
Tel
028-82253651 18140204969
Email
sales@refmedic.com
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China
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Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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China
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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0731-85526065 13308475853
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China
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
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China
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BioBioPha Co., Ltd.
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0871-65217109 13211707573;
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0871-65215563
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y.liu@mail.biobiopha.com
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China
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ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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021-55068248
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shyysw007@163.com
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China
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Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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+86-28-82633165
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cwb1@biopurify.cn
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China
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Shanghai Tauto Biotech Co., Ltd.
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021-51320588
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0086-21-51320502
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tauto@tautobiotech.com
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China
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AdooQ BioScience, LLC
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+1 (866) 930-6790
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+1 (866) 333-9607
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info@adooq.com
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United States
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View Lastest Price from (+)-Piresil-4-O-beta-D-glucopyraside manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
(+)-Piresil-4-O-beta-D-glucopyraside 69251-96-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-25
Shanghai Standard Technology Co., Ltd.
Product
Pinoresinol 4-O-beta-D-glucopyranoside 69251-96-3
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-03-11
Career Henan Chemical Co
Product
(+)-Piresil-4-O-beta-D-glucopyraside 69251-96-3
Price
US $6.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1kg, 5kg ,50kg
Release date
2020-03-09

69251-96-3, (+)-Piresil-4-O-beta-D-glucopyrasideRelated Search:


  • (+)-Piresil-4-O-beta-D-glucopyraside
  • Pinoresinol 4-O-beta-D-glucopyranoside
  • Pinoresinol 4-O-glucoside
  • (+)-pinoresinol-β-D-glucoside
  • (+)-Piresil-4-O-β-D-glucopyraside
  • 3,5-dibromo-benzoic acid,3,5-dibromobenzoic acid
  • (+)-pinoresinol-4-O-β-D-glucopyranoside
  • (+)-pinoresinol-β-D-glucoside(+)-pinoresinol-4-O-beta-D-glucopyranoside
  • (+)-Pinoresinol-4-O-β-D-glucopyraside
  • Pinoresinol 4-glucoside
  • 4-[(1S,3aR,4S,6aR)-4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H- furo[3,4-c]furan-1-yl]-2-methoxyphenyl β-D-glucopyranoside
  • (+)-pinor
  • β-D-Glucopyranoside, 2-methoxy-4-[(1S,3aR,4S,6aR)-tetrahydro-4-(4-hydroxy-3-methoxyphenyl)-1H,3H-furo[3,4-c]furan-1-yl]phenyl
  • (+)-pinoresinol-4-O-beta-D-glucopyranoside
  • 4-[(1S,3aR,4S,6aR)-4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-2-methoxyphenylβ-D-glucopyranoside
  • Pinoresinol 4-O-β-D-glucopyranoside
  • Pinoresinol-4-O-β-D-glucopyraside
  • phosphodiesterase,Inhibitor,Pinoresinol 4 O β D glucopyranoside,lignans,Pinoresinol 4OβDglucopyranoside,inhibit,cAMP,furofuran type
  • Terpineol-4-o- β- D-glucoside
  • (2S,3R,4S,5S,6R)-2-(4-((1S,3aR,4S,6aR)-4-(4-Hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)-2-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Pinoresinol 4-glucoside-RM
  • Pinoresinol 4-O-β-D-glucopyranoside, 10 mM in DMSO
  • (+)-pinoresinol-b-D-glucoside
  • PINORESINOL 4-O-GLUCOSIDE 98%
  • (+)-pinoresinol-β-D-glucoside
  • 69251-96-3
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Lignans