(+)-Piresil-4-O-beta-D-glucopyraside
- Product Name
- (+)-Piresil-4-O-beta-D-glucopyraside
- CAS No.
- 69251-96-3
- Chemical Name
- (+)-Piresil-4-O-beta-D-glucopyraside
- Synonyms
- (+)-pinor;Pinoresinol 4-glucoside;Pinoresinol 4-O-glucoside;Pinoresinol 4-glucoside-RM;(+)-pinoresinol-β-D-glucoside;Terpineol-4-o- β- D-glucoside;(+)-pinoresinol-b-D-glucoside;PINORESINOL 4-O-GLUCOSIDE 98%;(+)-pinoresinol-β-D-glucoside;(+)-Piresil-4-O-β-D-glucopyraside
- CBNumber
- CB62519179
- Molecular Formula
- C26H32O11
- Formula Weight
- 520.53
- MOL File
- 69251-96-3.mol
(+)-Piresil-4-O-beta-D-glucopyraside Property
- Melting point:
- 102-104 °C(Solv: methanol (67-56-1))
- Boiling point:
- 752.5±60.0 °C(Predicted)
- Density
- 1.418±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- Solid
- pka
- 9.84±0.35(Predicted)
- color
- White to light yellow
- InChIKey
- QLJNETOQFQXTLI-DUAOPOKGNA-N
- SMILES
- O(C1=C(C=CC([C@H]2OC[C@]3([H])[C@@H](C4C=CC(O)=C(OC)C=4)OC[C@]23[H])=C1)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C |&1:6,9,11,23,27,28,29,31,33,r|
N-Bromosuccinimide Price
- Product number
- PHL84251
- Product name
- Pinoresinol 4-glucoside
- Purity
- phyproof<SUP>®</SUP> Reference Substance
- Packaging
- 10 mg
- Price
- $408
- Updated
- 2025/07/31
- Product number
- 300794
- Product name
- Pinoresinol 4-O-glucoside
- Packaging
- 20mg
- Price
- $722
- Updated
- 2021/12/16
- Product number
- N2022
- Product name
- (+)-Piresil-4-O-beta-D-glucopyraside
- Packaging
- 20mg
- Price
- $500
- Updated
- 2021/12/16
- Product number
- AS111007
- Product name
- (+)-pinoresinol-β-D-glucoside
- Purity
- 97%
- Packaging
- 5mg
- Price
- $101
- Updated
- 2021/12/16
- Product number
- 2972
- Product name
- Pinoresinol-beta-D-glucoside
- Packaging
- 5mg
- Price
- $145
- Updated
- 2021/12/16
(+)-Piresil-4-O-beta-D-glucopyraside Chemical Properties,Usage,Production
Chemical Properties
Soluble in methanol, ethanol, DMSO and other organic solvents, derived from Forsythia.
Uses
(+)-Piresil-4-O-beta-D-glucopyraside is used for content determination/identification/pharmacological experiments, etc.
Definition
ChEBI: (+)-Pinoresinol 4-O-glucoside is a lignan and a glycoside.
Biological Activity
Pinoresinol 4-O-β-D-glucopyranoside ((+)-Pinoresinol 4-O-β-D-glucopyranoside) is the main active furofuranoside lignan in Forsythia. It has antioxidant, hypotensive and cyclic adenosine monophosphate (cAMP) phosphodiesterase inhibitory effects.
in vivo
Pinoresinol 4-O-β-D-glucopyranoside (50 mg/kg; p.o.; 20 days for hepatoprotective activity test, 10 days for antihyperglycaemic activity test) exhibits hepatoprotective activity by lowering AST and ALT levels in CCl4 (HY-Y0298)-induced hepatotoxicity mice, and shows antihyperglycaemic activity by causing a prominent decline in serum glucose level and a promising elevation in insulin level in Streptozotocin (HY-13753)-treated mice[4].
Pinoresinol 4-O-β-D-glucopyranoside (25-50 mg/kg; p.o.; twice with the second dose 1 h before pilocarpine injection) ameliorates the seizures in a dose-dependent manner in lithium/Pilocarpine (HY-B0726A)-induced epileptic seizures rats, manifested by retarding seizure onset, reducing the number of rats developing seizures, and enhancing the survival of animals after seizure exposure[7].
| Animal Model: | Male Swiss albino mice (weight: 27-30 g), CCl4-induced hepatotoxicity model and Streptozotocin-induced hyperglycaemia model[4] |
| Dosage: | 50 mg/kg b.w. |
| Administration: | Oral gavage (p.o.), 20 days in the hepatotoxicity experiment; 10 days in the hyperglycaemia experiment |
| Result: | Led to a 33.94% decline in AST, a 3.01% decline in ALT, and a 49.96% decline in LPO levels (in the CCl4-induced hepatotoxicity model). Significantly enhanced CAT, SOD, and TAS levels by 130%, 90.45%, and 61.39% respectively compared to the CCl4-treated group (in the CCl4-induced hepatotoxicity model). Caused a 37.83% reduction in serum glucose level and a 25.37% increase in insulin level (in the Streptozotocin-induced hyperglycaemia model). Reduced lipid peroxide levels by 51.77% and increased serum levels of CAT, SOD, and TAS by 93.02%, 70.79%, and 101.90%, respectively (in the Streptozotocin-induced hyperglycaemia model). |
(+)-Piresil-4-O-beta-D-glucopyraside Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (+)-Piresil-4-O-beta-D-glucopyraside manufacturers
- Product
- (+)-Piresil-4-O-beta-D-glucopyraside 69251-96-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-25
- Product
- Pinoresinol 4-O-beta-D-glucopyranoside 69251-96-3
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-03-11
- Product
- (+)-Piresil-4-O-beta-D-glucopyraside 69251-96-3
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg, 5kg ,50kg
- Release date
- 2020-03-09