ChemicalBook > CAS DataBase List > 6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one

6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one

Product Name
6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
CAS No.
67927-44-0
Chemical Name
6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
Synonyms
6-Bromo-3-methylbenzoxazol-2(3H)-one;6-bromo-3-methyl-1,3-benzoxazol-2-one;2(3H)-Benzoxazolone, 6-bromo-3-methyl-;6-Bromo-3-methylbenzo[d]oxazol-2(3H)-one;6-Bromo-3-methyl-1,3-benzoxazol-2(3H)-one, 97%;6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
CBNumber
CB62527198
Molecular Formula
C8H6BrNO2
Formula Weight
228.04
MOL File
67927-44-0.mol
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6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one Property

Melting point:
143-144 °C(Solv: hexane (110-54-3))
Boiling point:
298.2±42.0 °C(Predicted)
Density 
1.710±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
Powder
pka
-1.30±0.20(Predicted)
color 
Off-white
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Safety

HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B293170
Product name
6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
Packaging
5mg
Price
$45
Updated
2021/12/16
TRC
Product number
B293170
Product name
6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
Packaging
10mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
8001AE
Product name
6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
Packaging
1g
Price
$371
Updated
2021/12/16
Matrix Scientific
Product number
056372
Product name
6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one
Purity
>95%
Packaging
500mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0061032
Product name
6-BROMO-3-METHYL-2,3-DIHYDRO-1,3-BENZOXAZOL-2-ONE
Purity
95.00%
Packaging
1G
Price
$721.57
Updated
2021/12/16
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6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one Chemical Properties,Usage,Production

Synthesis

19932-85-5

74-88-4

67927-44-0

Example 3: Scheme B2; To a solution of 6-bromobenzo[d]oxazol-2(3H)-one (1 eq., 23 mmol, 5.0 g) in acetone (230 ml) was sequentially added potassium carbonate (1.5 eq., 35 mmol, 5.0 g) and iodomethane (1.2 eq., 28 mmol, 4.0 g); The reaction mixture was stirred for 4 hours at room temperature. After completion of the reaction, the acetone solvent was partially concentrated under reduced pressure; the concentrated mixture was poured into 1N HCl aqueous solution and the precipitate was collected by filtration and washed sequentially with water, isopropanol and isopropyl ether to afford 6-bromo-3-methylbenzo[d]oxazol-2(3H)-one (4.22 g, Yield = 79%, Purity (LC) = 99%) as a pinkish pink powder.

References

[1] Patent: WO2008/37784, 2008, A1. Location in patent: Page/Page column 35-36
[2] Patent: US2016/289238, 2016, A1. Location in patent: Paragraph 0322; 0323

6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-one Suppliers

Meryer (Shanghai) Chemical Technology Co., Ltd.
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Thermo Fisher Scientific
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800-810-5118
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+86-10-84193589
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cnchemical@thermofisher.com
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China
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Bide Pharmatech Ltd.
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67927-44-0, 6-Bromo-3-methyl-2,3-dihydro-1,3-benzoxazol-2-oneRelated Search:


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