ChemicalBook > CAS DataBase List > BID

BID

Product Name
BID
CAS No.
1416258-16-6
Chemical Name
BID
Synonyms
BID;FP497;p22 BID;MGC42355;MGC15319;((plusmn))-BI-D;BID from mouse;BID, GST tagged human;BH3-interacting domain death agonist;ANTI-MOUSE BID (S61) antibody produced in rabbit
CBNumber
CB6253440
Molecular Formula
C25H27NO4
Formula Weight
405.49
MOL File
1416258-16-6.mol
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BID Property

Boiling point:
587.3±50.0 °C(Predicted)
Density 
1.203±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMSO: ≥ 100 mg/mL (246.62 mM)
form 
buffered aqueous solution
pka
1.38±0.30(Predicted)
color 
Light yellow to yellow
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Safety

WGK Germany 
-
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
B1095-03A
Product name
BID
Packaging
50ug
Price
$297
Updated
2021/12/16
Usbiological
Product number
B1095-04A
Product name
BID
Packaging
50ug
Price
$297
Updated
2021/12/16
Usbiological
Product number
153676
Product name
BH3 Interacting Domain Death Agonist
Packaging
10ug
Price
$316
Updated
2021/12/16
Usbiological
Product number
153677
Product name
BH3 Interacting Domain Death Agonist
Packaging
10ug
Price
$343
Updated
2021/12/16
Usbiological
Product number
153678
Product name
BH3 Interacting Domain Death Agonist
Packaging
10ug
Price
$343
Updated
2021/12/16
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BID Chemical Properties,Usage,Production

Uses

(±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site. IC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) [1] Target: integrase inhibitor in vitro: Approximately 2.4–2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160–200 nM, in Psip1 and double-KO cells [1].

References

[1] Wang H, et al. HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor. Nucleic Acids Res. 2012 Dec;40(22):11518-30. DOI:10.1093/nar/gks913
[2] Fader LD, et al. Minimizing the Contribution of Enterohepatic Recirculation to Clearance in Rat for the NCINI Class of Inhibitors of HIV. ACS Med Chem Lett. 2014 Apr 16;5(6):711-6. DOI:10.1021/ml500110j

BID Preparation Products And Raw materials

Raw materials

Preparation Products

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BID Suppliers

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1416258-16-6, BIDRelated Search:


  • BID
  • BID from mouse
  • ANTI-MOUSE BID (S61) antibody produced in rabbit
  • BH3-interacting domain death agonist
  • p22 BID
  • FP497
  • MGC15319
  • MGC42355
  • BID, GST tagged human
  • ((plusmn))-BI-D
  • 3-Quinolineacetic acid, 4-(3,4-dihydro-2H-1-benzopyran-6-yl)-α-(1,1-dimethylethoxy)-2-methyl-
  • Recombinant Human BID/BH3-interacting domain death agonist protein Protein, No Tag
  • 1416258-16-6
  • Apoptosis and Cell Cycle
  • Bcl-2 Family Proteins
  • Cell Signaling and Neuroscience