ChemicalBook > CAS DataBase List > RWJ 50271
RWJ 50271
- Product Name
- RWJ 50271
- CAS No.
- 162112-37-0
- Chemical Name
- RWJ 50271
- Synonyms
- RWJ 50271;RWJ 50271, 10 mM in DMSO;N-(3-Hydroxypropyl)-5-methyl-1-(4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-1H-pyrazole-4-carboxamide;N-(3-hydroxypropyl)-5-methyl-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]pyrazole-4-carboxamide;1H-Pyrazole-4-carboxamide, N-(3-hydroxypropyl)-5-methyl-1-[4-[3-(trifluoromethyl)phenyl]-2-thiazolyl]-;N-(3-Hydroxypropyl)-5-methyl-1-[-4-[3-(trifluoromethyl)phenyl)]-2-thiazolyl]-1H-pyrazole-4-carboxamide;N-(3-Hydroxypropyl)-5-methyl-1-(4-(3-(trifluoromethyl)phenyl)thiazol-2-yl)-1H-pyrazole-4-carboxamide , RWJ 50271;inhibit,RWJ 50271,arthritis,RWJ-50271,organ,Inhibitor,transplantation,cell,Integrin,RWJ50271,rheumatoid,adhesion,molecules
- CBNumber
- CB62538284
- Molecular Formula
- C18H17F3N4O2S
- Formula Weight
- 410.41
- MOL File
- 162112-37-0.mol
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RWJ 50271 Property
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- Store at RT
- solubility
- <41.04mg/ml in DMSO
- pka
- 14.28±0.46(Predicted)
- form
- Solid
- color
- White to off-white
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
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N-Bromosuccinimide Price
Tocris
- Product number
- 4227
- Product name
- RWJ50271
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $212
- Updated
- 2021/12/16
Tocris
- Product number
- 4227
- Product name
- RWJ50271
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $854
- Updated
- 2021/12/16
TRC
- Product number
- R925205
- Product name
- RWJ50271
- Packaging
- 10mg
- Price
- $200
- Updated
- 2021/12/16
Usbiological
- Product number
- 256539
- Product name
- RWJ 50271
- Packaging
- 10mg
- Price
- $466
- Updated
- 2021/12/16
TRC
- Product number
- R925205
- Product name
- RWJ50271
- Packaging
- 50mg
- Price
- $810
- Updated
- 2021/12/16
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RWJ 50271 Chemical Properties,Usage,Production
Uses
RWJ 50271 is an inhibitor of LFA-1/ICAM-1 mediated cell adhesion.
in vivo
RWJ 50271 (50 mg/kg; p.o.) is effective in animal model of inflammation[1].
| Animal Model: | Mice, the delayed-type hypersensitivity [DTH] reaction model[1] |
| Dosage: | 50 mg/kg |
| Administration: | Oral administration |
| Result: | Significantly reduced foot pad swelling (>50%) 48 h after the challenge. |
RWJ 50271 Preparation Products And Raw materials
Raw materials
Preparation Products
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RWJ 50271 Suppliers
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