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2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester

Product Name
2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester
CAS No.
1246372-66-6
Chemical Name
2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester
Synonyms
2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile;2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile;3-Pyridinecarbonitrile, 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
CBNumber
CB62538385
Molecular Formula
C12H16BN3O2
Formula Weight
245.09
MOL File
1246372-66-6.mol
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2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester Property

storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
InChI
InChI=1S/C12H16BN3O2/c1-11(2)12(3,4)18-13(17-11)9-5-8(6-14)10(15)16-7-9/h5,7H,1-4H3,(H2,15,16)
InChIKey
KRNXYPYYVHFVQS-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(B2OC(C)(C)C(C)(C)O2)C=C1C#N
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
BOR0006287
Product name
2-AMINO-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)NICOTINONITRILE
Purity
95.00%
Packaging
1G
Price
$592.2
Updated
2021/12/16
AK Scientific
Product number
3810DT
Product name
2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
Packaging
5g
Price
$2085
Updated
2021/12/16
Crysdot
Product number
CD11316942
Product name
2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
Purity
95+%
Packaging
5g
Price
$2176
Updated
2021/12/16
Alichem
Product number
1246372666
Product name
2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
Packaging
1g
Price
$684.52
Updated
2021/12/16
Crysdot
Product number
CD11316942
Product name
2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
Purity
95+%
Packaging
1g
Price
$724
Updated
2021/12/16
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2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester Chemical Properties,Usage,Production

Synthesis

2-amino-5-bromonicotinonitrile (50 g, 0.224 mol), bis (pinacolato) diboron (85.6 g, 0.337 mol), KOAc (44.1 g, 0.449 mol) and Pd (dppf) Cl2. CH2C12 (2.77 g, 3.4 mmol) was charged into a flask. Dioxane (400 mL) was added. The reaction mixture was stirred at 100 ℃ for 2 h under Ar. When LC-MS indicated that the reaction was completed, the mixture was cooled to room temperature. Subsequently, the mixture was filtered through diatomite, concentrated, diluted with a mixture of ethyl acetate and hexane (3:1, 1000 mL), filtered through silica gel (300-400 mesh), concentrated, crystallized and dried to give 2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester (32 g, 66%) as a white solid.

2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester Suppliers

Tetranov Biopharm
Tel
13526569071
Email
sales@leadmedpharm.com
Country
China
ProdList
7906
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
86(512)5235 8471 17715136450
Fax
86(512)5235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
4169
Advantage
58
DONGSHENG CHIRAL PHARMA
Tel
180000000
Email
3755454181@qq.com
Country
China
ProdList
420
Advantage
55
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4852
Advantage
55
SuZhou ShiYa Biopharmaceuticals, Inc.
Tel
0512-52358471 17715136450
Fax
05125235 6881
Email
sales@shiyabiopharm.com
Country
China
ProdList
13496
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
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58
Yujinpharma(Tianjin) Technology Co.,Ltd.
Tel
13370351217 kungfu1217@1
Fax
QQ1400885609
Email
kungfu1217@163.com
Country
China
ProdList
9037
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000
Email
admin@jingshipharmatech.com
Country
China
ProdList
9972
Advantage
58
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View Lastest Price from 2-Amino-3-cyanopyridine-5-boronic Acid Pinacol Ester manufacturers

Career Henan Chemical Co
Product
2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile 1246372-66-6
Price
US $2.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
ask
Release date
2020-01-08

1246372-66-6, 2-Amino-3-cyanopyridine-5-boronic Acid Pinacol EsterRelated Search:


  • 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)nicotinonitrile
  • 3-Pyridinecarbonitrile, 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-carbonitrile
  • 1246372-66-6