O-DesMethyl TraMadol Hydrochloride
- Product Name
- O-DesMethyl TraMadol Hydrochloride
- CAS No.
- 185453-02-5
- Chemical Name
- O-DesMethyl TraMadol Hydrochloride
- Synonyms
- Tramadol EP Impurity D;Tramadol EP Impurity D HCl;TraMadol Hydrochloride IMpurity-D(EP);O-Desmethyl-cis-tramadol (hydrochloride);Tramadol Impurity 4（Tramadol EP Impurity D）;O-DesMethyl TraMadol Hydrochloride Impurity;Tramadol EP Impurity D HCl ( and Enantiomer);O-Desmethyl-cis-tramadol (hydrochloride) (CRM);(±)-(cis)-O-Desmethyl cis-tramadol hydrochloride;Tramadol Hydrochloride Impurity D as Hydrochloride
- CBNumber
- CB62544072
- Molecular Formula
- C15H24ClNO2
- Formula Weight
- 285.80956
- MOL File
- 185453-02-5.mol
O-DesMethyl TraMadol Hydrochloride Property
- Melting point:
- 219-221?C
- storage temp.
- -20°C Freezer
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to off-white
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 13976
- Product name
- O-Desmethyl-cis-tramadol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $79
- Updated
- 2023/06/20
- Product number
- 13976
- Product name
- O-Desmethyl-cis-tramadol (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $348
- Updated
- 2023/06/20
- Product number
- 18751
- Product name
- O-Desmethyl-cis-tramadol (hydrochloride) (CRM)
- Packaging
- 1mg
- Price
- $79
- Updated
- 2023/06/20
- Product number
- 33363
- Product name
- O-Desmethyltramadol hydrochloride
- Packaging
- 1mg
- Price
- $890
- Updated
- 2021/12/16
O-DesMethyl TraMadol Hydrochloride Chemical Properties,Usage,Production
Description
O-Desmethyl-cis-tramadol (hydrochloride) (CRM) (Item No. 18751) is a certified reference material that is structurally categorized as an opioid. It is the main metabolite of cis-tramadol (Item Nos. ISO60149 | 15919). O-Desmethyl-cis-tramadol has ~400-500-fold higher affinity for μ-opioid receptors than the parent compound. However, O-desmethyl-cis-tramadol poorly suppresses the human serotonin transporter, unlike cis-tramadol. This product is intended for research and forensic applications.
Chemical Properties
White Solid
Uses
A metabolite of Tramadol, an analgesic.
References
[1] MADELEINE RAMONA VOLZ Bjoern M. Development of a non-radioactive mass spectrometry-based binding assay at the μ-opioid receptor and its application for the determination of the binding affinities of 17 opiates/opioids as well as of the designer opioid isotonitazene and five further 2-benzylbenzimidazoles[J]. Analytica Chimica Acta, 2022, 1219: Article 339978. DOI: 10.1016/j.aca.2022.339978
[2] ATSUSHI NAKAMURA. Changes in the rewarding effects induced by tramadol and its active metabolite M1 after sciatic nerve injury in mice.[J]. Psychopharmacology, 2008, 200 3: 307-316. DOI: 10.1007/s00213-008-1180-1
[3] W. WU. Metabolism of the analgesic drug, tramadol hydrochloride, in rat and dog[J]. Xenobiotica, 2001, 31 1: 423-441. DOI: 10.1080/00498250110057378