ChemicalBook > CAS DataBase List > trans-Ned 19

trans-Ned 19

Product Name
trans-Ned 19
CAS No.
1354235-96-3
Chemical Name
trans-Ned 19
Synonyms
trans-Ned 19;transNed 19,trans Ned 19;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-
CBNumber
CB62546793
Molecular Formula
C30H31FN4O3
Formula Weight
514.59
MOL File
1354235-96-3.mol
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trans-Ned 19 Property

Melting point:
168-173°C
Boiling point:
715.1±60.0 °C(Predicted)
Density 
1.316±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Methanol
form 
Solid
pka
2.17±0.40(Predicted)
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17527
Product name
trans-Ned-19
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
17527
Product name
trans-Ned-19
Purity
≥98%
Packaging
5mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
17527
Product name
trans-Ned-19
Purity
≥98%
Packaging
10mg
Price
$321
Updated
2024/03/01
Tocris
Product number
3954
Product name
trans-Ned19
Purity
≥98%(HPLC)
Packaging
10
Price
$335
Updated
2021/12/16
TRC
Product number
N388750
Product name
trans-Ned-19
Packaging
50mg
Price
$1135
Updated
2021/12/16
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trans-Ned 19 Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Uses

trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.

Definition

ChEBI: Trans-Ned 19 is a member of the class of beta-carbolines that is 2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid in which one of the methylene protons at position 1 has been replaced by a 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-methoxyphenyl group. It has a role as a nicotinic acid adenine dinucleotide phosphate receptor antagonist. It is a member of beta-carbolines, an alpha-amino acid, a monomethoxybenzene, a member of monofluorobenzenes and a N-arylpiperazine.

storage

Store at -20°C

trans-Ned 19 Preparation Products And Raw materials

Raw materials

Preparation Products

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trans-Ned 19 Suppliers

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1354235-96-3, trans-Ned 19Related Search:


  • trans-Ned 19
  • (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid
  • (1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
  • 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-
  • transNed 19,trans Ned 19
  • 1354235-96-3
  • Aromatics, Heterocycles, Indole Derivatives, Inhibitors, Fluorescent Labels & Indicators, Pharmaceuticals, Intermediates & Fine Chemicals
  • Aromatics
  • Fluorescent Labels & Indicators
  • Heterocycles
  • Indole Derivatives
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals