ChemicalBook > CAS DataBase List > N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide

Product Name
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
CAS No.
857679-55-1
Chemical Name
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
Synonyms
CS-261;INCB 8761;PF-4136309;(Rac)-PF-4136309;PF-4136309(INCB 8761);(1341224-83-6) incb 8761;(S)-N-(2-(3-((4-Hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide;N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide;Benzamide, N-[2-[(3S)-3-[[4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-
CBNumber
CB62554338
Molecular Formula
C29H31F3N6O3
Formula Weight
568.59
MOL File
857679-55-1.mol
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N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Property

Boiling point:
712.2±60.0 °C(Predicted)
Density 
1.40
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (175.87 mM);Ethanol: 100 mg/mL (175.87 mM)
pka
13.17±0.46(Predicted)
form 
Solid
color 
Light yellow to yellow
Water Solubility 
Water: Insoluble
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
474115
Product name
INCB 8761
Packaging
100mg
Price
$1932
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0001391
Product name
N-[2-[(3S)-3-[[4-HYDROXY-4-[5-(PYRIMIDIN-2-YL)PYRIDIN-2-YL]CYCLOHEXYL]AMINO]PYRROLIDIN-1-YL]-2-OXOETHYL]-3-(TRIFLUOROMETHYL)BENZAMIDE
Purity
95.00%
Packaging
5MG
Price
$345.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb181258
Product name
INCB8761
Purity
>98%
Packaging
100mg
Price
$838.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb181258
Product name
INCB8761
Purity
>98%
Packaging
250mg
Price
$1431.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb181258
Product name
INCB8761
Purity
>98%
Packaging
1000mg
Price
$2691.1
Updated
2021/12/16
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N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Chemical Properties,Usage,Production

Uses

PF 4136309 is a CCR5 receptor antagonists that contributes to the treatment of rheumatoid arthritis.

N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide Suppliers

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View Lastest Price from N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide manufacturers

Career Henan Chemical Co
Product
N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide 857679-55-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200kg
Release date
2020-01-09

857679-55-1, N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamideRelated Search:


  • N-[2-[(3S)-3-[[4-Hydroxy-4-[5-(pyrimidin-2-yl)pyridin-2-yl]cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
  • INCB 8761
  • PF-4136309
  • PF-4136309(INCB 8761)
  • CS-261
  • (1341224-83-6) incb 8761
  • Benzamide, N-[2-[(3S)-3-[[4-hydroxy-4-[5-(2-pyrimidinyl)-2-pyridinyl]cyclohexyl]amino]-1-pyrrolidinyl]-2-oxoethyl]-3-(trifluoromethyl)-
  • (S)-N-(2-(3-((4-Hydroxy-4-(5-(pyrimidin-2-yl)pyridin-2-yl)cyclohexyl)amino)pyrrolidin-1-yl)-2-oxoethyl)-3-(trifluoromethyl)benzamide
  • (Rac)-PF-4136309
  • 857679-55-1
  • C29H31F3N6O3