2-(1H-indol-1-yl)ethanol

Product Name: 2-(1H-indol-1-yl)ethanol
CAS No.: 121459-15-2
Chemical Name: 2-(1H-indol-1-yl)ethanol
Synonyms: 1H-Indole-1-ethanol;2-(INDOL-1-YL)ETHANOL;2-(1H-indol-1-yl)ethanol;2-(1H-indol-1-yl)ethan-1-ol;2-(1H-i2-(1H-indol-1-yl)ethanolndol-1-yl)ethanol
CBNumber: CB62561123
Molecular Formula: C10H11NO
Formula Weight: 161.2
MOL File: 121459-15-2.mol

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2-(1H-indol-1-yl)ethanol Property

Melting point:: 42-43 °C
Boiling point:: 141-142 °C(Press: 2.5 Torr)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: 14.87±0.10(Predicted)
Appearance: Light yellow to yellow Liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PH017555
Product name: 2-(1H-Indol-1-yl)ethanol
Purity: AldrichCPR
Packaging: 500mg
Price: $241
Updated: 2023/06/20

TRC

Product number: I628108
Product name: 2-(1H-Indol-1-yl)ethanol
Packaging: 10mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: 3893AA
Product name: 2-(1H-Indol-1-yl)ethanol
Packaging: 100mg
Price: $194
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0387488
Product name: 2-(1H-INDOL-1-YL)ETHANOL
Purity: 95.00%
Packaging: 5MG
Price: $498.36
Updated: 2021/12/16

Ambeed

Product number: A742354
Product name: 2-(1H-Indol-1-yl)ethanol
Purity: 97%
Packaging: 100mg
Price: $67
Updated: 2021/12/16

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2-(1H-indol-1-yl)ethanol Chemical Properties,Usage,Production

Synthesis

120-72-9

540-51-2

121459-15-2

The general procedure for the synthesis of 2-(1H-indol-1-yl)ethanol from indole and 2-bromoethanol is as follows: the preparation of methyl 2-[4-[2-indolyl]ethoxy]phenylthio-butanoate (ST1983) is described in Example 8. First, the intermediate 1-(2-hydroxyethyl)indole was prepared in a procedure that referenced the method reported in J. Med. Chem. 1998,41/10,1619-1639, but with the reaction time adjusted to 30 h (30 min in the original literature). The procedure was as follows: indole (5.0 g, 42.7 mmol) was dissolved in 50 ml of anhydrous DMSO, KOH (3.6 g, 64.1 mmol) and 2-bromoethanol (6.4 g, 51.3 mmol) were added and the reaction was carried out at 25-30 °C. Finally, 5 g of oily product was obtained in 73% yield.

References

[1] Organic and Biomolecular Chemistry, 2013, vol. 11, # 28, p. 4569 - 4572
[2] Patent: WO2004/56355, 2004, A1. Location in patent: Page/Page column 23
[3] Angewandte Chemie - International Edition, 2014, vol. 53, # 20, p. 5142 - 5146
[4] Angew. Chem., 2014, vol. 126, # 20, p. 5237 - 5241,5
[5] Chemical Communications, 2015, vol. 52, # 2, p. 346 - 349

2-(1H-indol-1-yl)ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(1H-indol-1-yl)ethanol Suppliers

China 38 United States 2 Global 40

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121459-15-2, 2-(1H-indol-1-yl)ethanolRelated Search:

2-(1H-indol-1-yl)ethanol

2-(INDOL-1-YL)ETHANOL

1H-Indole-1-ethanol

2-(1H-i2-(1H-indol-1-yl)ethanolndol-1-yl)ethanol

2-(1H-indol-1-yl)ethan-1-ol

121459-15-2