2-(1H-indol-1-yl)ethanol
- Product Name
- 2-(1H-indol-1-yl)ethanol
- CAS No.
- 121459-15-2
- Chemical Name
- 2-(1H-indol-1-yl)ethanol
- Synonyms
- 1H-Indole-1-ethanol;2-(INDOL-1-YL)ETHANOL;2-(1H-indol-1-yl)ethanol;2-(1H-indol-1-yl)ethan-1-ol;2-(1H-i2-(1H-indol-1-yl)ethanolndol-1-yl)ethanol
- CBNumber
- CB62561123
- Molecular Formula
- C10H11NO
- Formula Weight
- 161.2
- MOL File
- 121459-15-2.mol
2-(1H-indol-1-yl)ethanol Property
- Melting point:
- 42-43 °C
- Boiling point:
- 141-142 °C(Press: 2.5 Torr)
- Density
- 1.11±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- form
- solid
- pka
- 14.87±0.10(Predicted)
- Appearance
- Light yellow to yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P391Collect spillage. Hazardous to the aquatic environment
N-Bromosuccinimide Price
- Product number
- PH017555
- Product name
- 2-(1H-Indol-1-yl)ethanol
- Purity
- AldrichCPR
- Packaging
- 500mg
- Price
- $241
- Updated
- 2023/06/20
- Product number
- I628108
- Product name
- 2-(1H-Indol-1-yl)ethanol
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 3893AA
- Product name
- 2-(1H-Indol-1-yl)ethanol
- Packaging
- 100mg
- Price
- $194
- Updated
- 2021/12/16
- Product number
- CHM0387488
- Product name
- 2-(1H-INDOL-1-YL)ETHANOL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $498.36
- Updated
- 2021/12/16
- Product number
- A742354
- Product name
- 2-(1H-Indol-1-yl)ethanol
- Purity
- 97%
- Packaging
- 100mg
- Price
- $67
- Updated
- 2021/12/16
2-(1H-indol-1-yl)ethanol Chemical Properties,Usage,Production
Synthesis
120-72-9
540-51-2
121459-15-2
The general procedure for the synthesis of 2-(1H-indol-1-yl)ethanol from indole and 2-bromoethanol is as follows: the preparation of methyl 2-[4-[2-indolyl]ethoxy]phenylthio-butanoate (ST1983) is described in Example 8. First, the intermediate 1-(2-hydroxyethyl)indole was prepared in a procedure that referenced the method reported in J. Med. Chem. 1998,41/10,1619-1639, but with the reaction time adjusted to 30 h (30 min in the original literature). The procedure was as follows: indole (5.0 g, 42.7 mmol) was dissolved in 50 ml of anhydrous DMSO, KOH (3.6 g, 64.1 mmol) and 2-bromoethanol (6.4 g, 51.3 mmol) were added and the reaction was carried out at 25-30 °C. Finally, 5 g of oily product was obtained in 73% yield.
References
[1] Organic and Biomolecular Chemistry, 2013, vol. 11, # 28, p. 4569 - 4572
[2] Patent: WO2004/56355, 2004, A1. Location in patent: Page/Page column 23
[3] Angewandte Chemie - International Edition, 2014, vol. 53, # 20, p. 5142 - 5146
[4] Angew. Chem., 2014, vol. 126, # 20, p. 5237 - 5241,5
[5] Chemical Communications, 2015, vol. 52, # 2, p. 346 - 349
2-(1H-indol-1-yl)ethanol Preparation Products And Raw materials
Raw materials
Preparation Products
2-(1H-indol-1-yl)ethanol Suppliers
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- 8485655694
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- Country
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