Fosravuconazole L-lysine ethanolate

Product Name: Fosravuconazole L-lysine ethanolate
CAS No.: 914361-45-8
Chemical Name: Fosravuconazole L-lysine ethanolate
Synonyms: E-1224 L-lysine ethanolate;BMS-379224 L-lysine ethanolate;Fosravuconazole L-lysine ethanolate;L-Lysine, coMpd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-Methyl-2-[(phosphonooxy)Methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile and ethanol (1:1:1) (9CI);(S)-2,6-Diaminohexanoic acid (((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate and ethanol salt;Fungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,parasitemia,inhibit,Fosravuconazole L lysine ethanolate,antifungal,Ravuconazole,Inhibitor,candidiasis,Fosravuconazole L-lysine
CBNumber: CB62563389
Molecular Formula: C31H40F2N7O8PS
Formula Weight: 739.73
MOL File: 914361-45-8.mol

More

Less

Fosravuconazole L-lysine ethanolate Property

storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (67.59 mM; Need ultrasonic)| (insoluble)
form: Solid
color: White to yellow
Water Solubility: Water : < 0.1 mg/mL (ultrasonic)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 10mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 25mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 50mg
Price: $1550
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 100mg
Price: $2350
Updated: 2021/12/16

More

Less

Fosravuconazole L-lysine ethanolate Chemical Properties,Usage,Production

Biological Activity

Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad-spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used in the study of candidiasis, onychomycosis and parasitic diseases.

in vitro

Fosravuconazole has potent in vitro antifungal activity against a wide range of fungal species, including Candida , Aspergillus , and Trichophyton species .

in vivo

Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain.

Animal Model:	Swiss female mice (20-24 g) inoculated with trypomastigotes (Y strain).
Dosage:	10 mg/kg, 20 mg/kg, 30 mg/kg, 40 mg/kg , 50 mg/kg
Administration:	Oral administration; daily; for 20 days
Result:	Suppressed the parasitemia and prevented death.

Fosravuconazole L-lysine ethanolate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Fosravuconazole L-lysine ethanolate Suppliers

China 19 United States 2 Global 21

Shanghai Fuhe Chemistry Technology Co., Ltd.

Tel: 0086-21-67651709
Fax: 0086-21-67651705
Email: cfx759@hotmail.com
Country: China
ProdList: 410
Advantage: 57

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4566
Advantage: 55

Shanghai eliv pharmaceutical Co.,Ltd.

Tel: 021-50158063
Fax: 021-6153 1846
Email: sales@elivpharma.com
Country: China
ProdList: 646
Advantage: 58

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2994
Advantage: 58

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7291
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Heze Development Zone chuangli Chemical Co., Ltd.

Tel: +86-530-529 6766，+86-15666160102 15666160102
Fax: 0530-529 6766
Email: info@chuangli-chem.com
Country: China
ProdList: 896
Advantage: 55

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

Shanghai Luofa Biochemical Technology Co., Ltd.

Tel: 021-51111890 15317326293
Email: sales@molnova.com
Country: China
ProdList: 4195
Advantage: 58

Chunchuang (Wuhan) Technology Co., Ltd

Tel: 15342225168
Email: yutianchun2007@126.com
Country: China
ProdList: 10003
Advantage: 58

914361-45-8, Fosravuconazole L-lysine ethanolateRelated Search:

L-Lysine, coMpd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-Methyl-2-[(phosphonooxy)Methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile and ethanol (1:1:1) (9CI)

Fosravuconazole L-lysine ethanolate

BMS-379224 L-lysine ethanolate

E-1224 L-lysine ethanolate

Fungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,parasitemia,inhibit,Fosravuconazole L lysine ethanolate,antifungal,Ravuconazole,Inhibitor,candidiasis,Fosravuconazole L-lysine

(S)-2,6-Diaminohexanoic acid (((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate and ethanol salt

914361-45-8

API