Fosravuconazole L-lysine ethanolate

Product Name: Fosravuconazole L-lysine ethanolate
CAS No.: 914361-45-8
Chemical Name: Fosravuconazole L-lysine ethanolate
Synonyms: E-1224 L-lysine ethanolate;BMS-379224 L-lysine ethanolate;Fosravuconazole L-lysine ethanolate;L-Lysine, coMpd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-Methyl-2-[(phosphonooxy)Methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile and ethanol (1:1:1) (9CI);(S)-2,6-Diaminohexanoic acid (((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate and ethanol salt;Fungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,parasitemia,inhibit,Fosravuconazole L lysine ethanolate,antifungal,Ravuconazole,Inhibitor,candidiasis,Fosravuconazole L-lysine
CBNumber: CB62563389
Molecular Formula: C31H40F2N7O8PS
Formula Weight: 739.73
MOL File: 914361-45-8.mol

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Fosravuconazole L-lysine ethanolate Property

storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (67.59 mM; Need ultrasonic)| (insoluble)
Water Solubility: Water : < 0.1 mg/mL (ultrasonic)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 10mg
Price: $500
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 25mg
Price: $950
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 50mg
Price: $1550
Updated: 2021/12/16

ChemScene

Product number: CS-0145609
Product name: Fosravuconazole(L-lysineethanolate)
Purity: 96.30%
Packaging: 100mg
Price: $2350
Updated: 2021/12/16

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Fosravuconazole L-lysine ethanolate Chemical Properties,Usage,Production

Biological Activity

Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad-spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used in the study of candidiasis, onychomycosis and parasitic diseases.

in vitro

Fosravuconazole has potent in vitro antifungal activity against a wide range of fungal species, including Candida , Aspergillus , and Trichophyton species .

in vivo

Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain.

Animal Model:	Swiss female mice (20-24 g) inoculated with trypomastigotes (Y strain).
Dosage:	10 mg/kg, 20 mg/kg, 30 mg/kg, 40 mg/kg , 50 mg/kg
Administration:	Oral administration; daily; for 20 days
Result:	Suppressed the parasitemia and prevented death.

Fosravuconazole L-lysine ethanolate Preparation Products And Raw materials

Raw materials

Preparation Products

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Fosravuconazole L-lysine ethanolate Suppliers

China 17 United States 2 Global 19

Shanghai Fuhe Chemistry Technology Co., Ltd.

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914361-45-8, Fosravuconazole L-lysine ethanolateRelated Search:

L-Lysine, coMpd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-Methyl-2-[(phosphonooxy)Methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile and ethanol (1:1:1) (9CI)

Fosravuconazole L-lysine ethanolate

BMS-379224 L-lysine ethanolate

E-1224 L-lysine ethanolate

Fungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,parasitemia,inhibit,Fosravuconazole L lysine ethanolate,antifungal,Ravuconazole,Inhibitor,candidiasis,Fosravuconazole L-lysine

(S)-2,6-Diaminohexanoic acid (((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate and ethanol salt

914361-45-8

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