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Fosravuconazole L-lysine ethanolate

Product Name
Fosravuconazole L-lysine ethanolate
CAS No.
914361-45-8
Chemical Name
Fosravuconazole L-lysine ethanolate
Synonyms
E-1224 L-lysine ethanolate;BMS-379224 L-lysine ethanolate;Fosravuconazole L-lysine ethanolate;L-Lysine, coMpd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-Methyl-2-[(phosphonooxy)Methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile and ethanol (1:1:1) (9CI);(S)-2,6-Diaminohexanoic acid (((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate and ethanol salt;Fungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,parasitemia,inhibit,Fosravuconazole L lysine ethanolate,antifungal,Ravuconazole,Inhibitor,candidiasis,Fosravuconazole L-lysine
CBNumber
CB62563389
Molecular Formula
C31H40F2N7O8PS
Formula Weight
739.73
MOL File
914361-45-8.mol
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Fosravuconazole L-lysine ethanolate Property

storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (67.59 mM; Need ultrasonic)| (insoluble)
Water Solubility 
Water : < 0.1 mg/mL (ultrasonic)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0145609
Product name
Fosravuconazole(L-lysineethanolate)
Purity
96.30%
Packaging
5mg
Price
$300
Updated
2021/12/16
ChemScene
Product number
CS-0145609
Product name
Fosravuconazole(L-lysineethanolate)
Purity
96.30%
Packaging
10mg
Price
$500
Updated
2021/12/16
ChemScene
Product number
CS-0145609
Product name
Fosravuconazole(L-lysineethanolate)
Purity
96.30%
Packaging
25mg
Price
$950
Updated
2021/12/16
ChemScene
Product number
CS-0145609
Product name
Fosravuconazole(L-lysineethanolate)
Purity
96.30%
Packaging
50mg
Price
$1550
Updated
2021/12/16
ChemScene
Product number
CS-0145609
Product name
Fosravuconazole(L-lysineethanolate)
Purity
96.30%
Packaging
100mg
Price
$2350
Updated
2021/12/16
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Fosravuconazole L-lysine ethanolate Chemical Properties,Usage,Production

Biological Activity

Fosravuconazole L-lysine ethanolate (BMS-379224 L-lysine ethanolate), a prodrug of Ravuconazole, is an orally active broad-spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used in the study of candidiasis, onychomycosis and parasitic diseases.

in vitro

Fosravuconazole has potent in vitro antifungal activity against a wide range of fungal species, including Candida , Aspergillus , and Trichophyton species .

in vivo

Fosravuconazole (E-1224; 10-50 mg/kg; oral administration; daily; for 20 days) treatment suppresses the parasitemia and prevents death in mice infected with the T. cruzi Y strain.

Animal Model: Swiss female mice (20-24 g) inoculated with trypomastigotes (Y strain).
Dosage: 10 mg/kg, 20 mg/kg, 30 mg/kg, 40 mg/kg , 50 mg/kg
Administration: Oral administration; daily; for 20 days
Result: Suppressed the parasitemia and prevented death.

Fosravuconazole L-lysine ethanolate Preparation Products And Raw materials

Raw materials

Preparation Products

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Fosravuconazole L-lysine ethanolate Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58

914361-45-8, Fosravuconazole L-lysine ethanolateRelated Search:


  • L-Lysine, coMpd. with 4-[2-[(1R,2R)-2-(2,4-difluorophenyl)-1-Methyl-2-[(phosphonooxy)Methoxy]-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile and ethanol (1:1:1) (9CI)
  • Fosravuconazole L-lysine ethanolate
  • BMS-379224 L-lysine ethanolate
  • E-1224 L-lysine ethanolate
  • Fungal,onychomycosis,Fosravuconazole Llysine ethanolate,Parasite,parasitemia,inhibit,Fosravuconazole L lysine ethanolate,antifungal,Ravuconazole,Inhibitor,candidiasis,Fosravuconazole L-lysine
  • (S)-2,6-Diaminohexanoic acid (((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate and ethanol salt
  • 914361-45-8
  • API