4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid

Product Name: 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid
CAS No.: 123654-26-2
Chemical Name: 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid
Synonyms: Prucalopride int;Prucalopride Impurity A;3-Benzothiazolecarboxaldehyde;4-Amino-5-chlorocoumaran-7-carboxylic Acid;4-amino-5-chloro-2.3-dihydro7-benzofuranoic acid;4-aMino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid;4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid;4-Amino-5-Chloro-2,3-Dihydrobenzofuran-4-Carboxylic Acid;7-Benzofurancarboxylic acid, 4-amino-5-chloro-2,3-dihydro-;4-AMino-5-chloro-2,3-dihydro-7-benzofurane karboxylic acid
CBNumber: CB62565893
Molecular Formula: C9H8ClNO3
Formula Weight: 213.62
MOL File: 123654-26-2.mol

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4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid Property

Melting point:: 242 °C(dec.)
Boiling point:: 406.5±45.0 °C(Predicted)
Density: 1.566
storage temp.: 2-8°C(protect from light)
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 4.45±0.20(Predicted)
color: Light Brown
InChI: InChI=1S/C9H8ClNO3/c10-6-3-5(9(12)13)8-4(7(6)11)1-2-14-8/h3H,1-2,11H2,(H,12,13)
InChIKey: KRMUVKSAOVLXLF-UHFFFAOYSA-N
SMILES: O1C2=C(C(O)=O)C=C(Cl)C(N)=C2CC1

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Safety

HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2918
Product name: 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid
Purity: >97.0%(HPLC)(T)
Packaging: 200mg
Price: $93
Updated: 2025/07/31

TCI Chemical

Product number: A2918
Product name: 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid
Purity: >97.0%(HPLC)(T)
Packaging: 1g
Price: $280
Updated: 2025/07/31

TRC

Product number: A603970
Product name: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylicAcid
Packaging: 2.5g
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: Y1132
Product name: 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid
Packaging: 5g
Price: $295
Updated: 2021/12/16

Chem-Impex

Product number: 31028
Product name: 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylicAcid,≥97%(HPLC)
Purity: ≥97%(HPLC)
Packaging: 1G
Price: $387.86
Updated: 2021/12/16

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4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid Chemical Properties,Usage,Production

Uses

4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic Acid, can be used as an intermediate for the synthesis of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation.

Synthesis

Firstly, adding methyl 4-(acetyl amino)-2-hydroxy-3-(2-hydroxy ethyl) benzoate into an organic solvent, adding triphenylphosphine and azo dioctyl phthalate diethyl ester, performing cyclization to obtain a methyl 4-acetamido-2,3-dihydro benzofuran-7-formate rough product, directly chloridizing the rough product by using N-chloro succinimide to obtain a rough product methyl 4-acetamide amino-5-chloro-7-benzofuran formate, and performing hydrolysis and purification to obtain a 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid pure product.

4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid Suppliers

Americas 1 China 160 Europe 1 India 17 Japan 1 United States 12 Global 192

Jinan Shuhong Biotechnology Co., Ltd.

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Adamas Reagent, Ltd.

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Accela ChemBio Co.,Ltd.

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View Lastest Price from 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid manufacturers

Sach biotech Co.,Ltd

Product: 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid 123654-26-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 800KGS/month
Release date: 2024-07-09

Henan Fengda Chemical Co., Ltd

Product: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid 123654-26-2
Price: US $6.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-28

Career Henan Chemical Co

Product: 4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid 123654-26-2
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-16

123654-26-2, 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acidRelated Search:

4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid

4-Amino-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylic acid

4-aMino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid

4-AMino-5-chloro-2,3-dihydro-7-benzofurane karboxylic acid

4-amino-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylic acid

Prucalopride Impurity A

Prucalopride int

4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic Acid &gt

7-Benzofurancarboxylic acid, 4-amino-5-chloro-2,3-dihydro-

4-Amino-5-chlorocoumaran-7-carboxylic Acid

4-Amino-5-chloro-2,3-dihydro-7-benzofurancarboxylic acid ISO 9001：2015 REACH

4-Amino-5-Chloro-2,3-Dihydrobenzofuran-4-Carboxylic Acid

"4-amino-5-chlor-2,3-dihydro-7-benzofurancarboxylic acid"Q: What is "4-amino-5-chlor-2,3-dihydro-7-benzofurancarboxylic acid" Q: What is the CAS Number of "4-amino-5-chlor-2,3-dihydro-7-benzofurancarboxylic acid" Q: What is the storage condition of "4-amino-5-chlor-2,3-dihydro-7-benzofurancarboxylic acid" Q: What are the applications of "4-amino-5-chlor-2,3-dihydro-7-benzofurancarboxylic acid"

3-Benzothiazolecarboxaldehyde

4-amino-5-chloro-2.3-dihydro7-benzofuranoic acid

123654-26-2

123456-26-2