ChemicalBook > CAS DataBase List > S 18986

S 18986

Product Name: S 18986
CAS No.: 175340-20-2
Chemical Name: S 18986
Synonyms: S 18986;(3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide;1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-
CBNumber: CB62565929
Molecular Formula: C10H12N2O2S
Formula Weight: 224.28
MOL File: 175340-20-2.mol

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S 18986 Property

Boiling point:: 399.9±45.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble to 50 mM in DMSO
form: Powder
pka: 9.88±0.20(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.04983
Product name: S18986 - CAS 175340-20-2 - Calbiochem
Packaging: 5MG
Price: $246
Updated: 2023/01/07

Cayman Chemical

Product number: 14937
Product name: S18986
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 14937
Product name: S18986
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 14937
Product name: S18986
Purity: ≥98%
Packaging: 10mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 14937
Product name: S18986
Purity: ≥98%
Packaging: 25mg
Price: $456
Updated: 2024/03/01

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S 18986 Chemical Properties,Usage,Production

Uses

S 18986 is a novel cognitive enhancer.

Biological Activity

Primary Target
AMPA', 'Reversible: yes

in vivo

S 18986 is robust memory-enhancing effects in middle-aged animals compared with aged ones. S 18986 shows antiamnesic properties in middle-aged rodents in spatial memory models ^[1].
S 18986 (5-50 mg/kg; i.p.) significantly increases both the induction and the maintenance of 4 and 20 bursts tetanus-evoked potentiation^[1].

Animal Model:	Middle-aged (14-15-months-old) mice^[1]
Dosage:	0.3, 1, and 10 mg/kg
Administration:	p.o.
Result:	Showed antiamnesic properties in middle-aged rodents.

S 18986 Preparation Products And Raw materials

Raw materials

Preparation Products

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S 18986 Suppliers

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175340-20-2, S 18986Related Search:

S 18986

1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aS)-

(3aS)-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4]benzothiadiazine 5,5-dioxide

175340-20-2