XANTHOPTERIN MONOHYDRATE Property

Melting point:

>300 °C(lit.)

storage temp. 

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility 

DMSO (Slightly), Methanol (Slightly), Water (Slightly)

form 

Solid

pka

6.59(at 20℃)

color 

Yellow to Dark Yellow

Sensitive 

Air Sensitive

Merck 

14,10064

Stability:

Hygroscopic

CAS DataBase Reference

5979-01-1(CAS DataBase Reference)

Safety

Safety Statements 

22-24/25

WGK Germany 

3

F 

10-23

HS Code 

29339980

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

XANTHOPTERIN MONOHYDRATE Chemical Properties,Usage,Production

Chemical Properties

yellow to orange crystalline powder

Uses

Biochemical research.

Uses

Xanthopterin (cas# 5979-01-1) is useful as a crystal nucleation of vinylidene chloride polymers.

Definition

Pigment found in the wings of butterflies; can be converted by yeast into folic acid.

Purification Methods

Purification is as for isoxanthopterin (see “Heterocyclic Compounds”, Chapter 4). It is crystallised by acidifying a hot ammoniacal solution with formic acid, and collecting the crystals by centrifugation followed by washing with EtOH, ether and drying at 100o in vacuo. Its RF values on paper chromatography are 0.15 (n-PrOH, 1% aqueous NH3, 2:1), 0.36 (n-BuOH/AcOH/H2O, 4:1:1) and 0.47 (3% aqueous NH3). [Inoue & Perrin J Chem Soc 260 1962, Inoue Tetrahedron 20 243 1964, see also Blakley Biochemistry of Folic Acid and Related Pteridines North Holland Publ Co, Amsterdam 1969, Beilstein 26 II 313, 26 III/IV 4000.]