(R)-N-Boc-3-aminomethylpiperidine

Uses

Product Name: (R)-N-Boc-3-aminomethylpiperidine
CAS No.: 140645-23-4
Chemical Name: (R)-N-Boc-3-aminomethylpiperidine
Synonyms: (R)-1-N-BOC-3-(AMINOMETHYL)PIPERIDINE;tert-Butyl 3-(aminomethyl)piperidine-1-carboxylate;tert-butyl (R)-3-(aminomethyl)piperidine-1-carboxylate;CAS:140645-23-4;3-(Aminomethyl)-1-Boc-piperidine;(R)-N-BOC-3-AMINOMETHYLPIPERIDINE;(R)-3-Aminomethyl-1-Boc-piperidine;(R)-1-BOC-3-(AMINOMETHYL)PIPERIDINE;(R)-1-N-BOC-PIPERIDINE-3-METHYLAMINE;(R)-3-AMINOMETHYL-1-N-BOC-PIPERIDINE
CBNumber: CB6256658
Molecular Formula: C11H22N2O2
Formula Weight: 214.3
MOL File: 140645-23-4.mol

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(R)-N-Boc-3-aminomethylpiperidine Property

Boiling point:: 299.4±13.0 °C(Predicted)
Density: 0.997g/mLat 25℃
refractive index: n20/D 1.473
Flash point:: >110°C
storage temp.: 2-8°C
pka: 10.12±0.29(Predicted)
form: Liquid
color: Clear colorless to pale yellow
CAS DataBase Reference: 140645-23-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn,N
Risk Statements: 22-50-36/37/38
Safety Statements: 26-61
RIDADR: UN 3082 9 / PGIII
WGK Germany: 3
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 735744
Product name: (R)-1-Boc-3-(aminomethyl)piperidine
Purity: 97%
Packaging: 500mg
Price: $105
Updated: 2023/06/20

TRC

Product number: B285103
Product name: (R)-tert-Butyl3-(Aminomethyl)piperidine-1-carboxylate
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 067100
Product name: (R)-1-N-Boc-3-(aminomethyl)piperidine
Purity: 98%
Packaging: 500mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-1-N6
Product name: (3R)-3-(Aminomethyl)piperidine, N1-Boc protected
Packaging: 1g
Price: $82
Updated: 2021/12/16

Matrix Scientific

Product number: 067100
Product name: (R)-1-N-Boc-3-(aminomethyl)piperidine
Purity: 98%
Packaging: 1g
Price: $99
Updated: 2021/12/16

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(R)-N-Boc-3-aminomethylpiperidine Chemical Properties,Usage,Production

Uses

(R)-1-Boc-3-aminomethylpiperidine is an important intermediate in the synthesis of many drugs. A series of checkpoint kinase 1 (CHK1) inhibitors have been synthesized using (R)-1-Boc-3-aminomethylpiperidine as a starting material, showing some efficacy in treating rheumatoid arthritis. A series of drugs for treating diseases related to MCH (melanin-concentrating hormone) have also been synthesized using this compound, showing some effectiveness in treating metabolic disorders. G-protein-coupled receptor (GPCR) agonists containing the 1-N-Boc-4-methylaminomethylpiperidine structural unit have been synthesized, which can be used to treat obesity and diabetes. A series of drugs for regulating metabolism and treating cardiovascular diseases have also been synthesized using (R)-1-Boc-3-aminomethylpiperidine.

(R)-N-Boc-3-aminomethylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-N-Boc-3-aminomethylpiperidine Suppliers

China 123 Europe 2 Germany 3 India 3 The Netherlands 1 United Kingdom 5 United States 32 Global 169

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 5000
Advantage: 55

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Sichuan Guanghan Bio-Tech Co., Ltd

Tel: +86-28-86127071
Fax: +86-28-86127072
Email: info@sino-produce.com
Country: China
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Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Adamas Reagent, Ltd.

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Fax: 021-64823266
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Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 15883
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
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Chembon Pharmaceutical Co., Ltd.

Tel: 028-84252981
Fax: +86-28-84252965
Email: sales@chembon.com.cn
Country: China
ProdList: 850
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View Lastest Price from (R)-N-Boc-3-aminomethylpiperidine manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-N-Boc-3-aminomethylpiperidine 140645-23-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-22

Honest Joy Holdings Limited

Product: (R)-1-Boc-3-(aminomethyl)piperidine 140645-23-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.7%
Supply Ability: 100 tons
Release date: 2022-01-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: (R)-N-Boc-3-aminomethylpiperidine 140645-23-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

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(R)-3-AMINOMETHYL-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(R)-3-AMINOMETHYL-1-N-BOC-PIPERIDINE

(R)-1-N-BOC-3-(AMINOMETHYL)PIPERIDINE

(R)-1-N-BOC-PIPERIDINE-3-METHYLAMINE

(R)-1-BOC-3-(AMINOMETHYL)PIPERIDINE

(R)-N-BOC-3-AMINOMETHYLPIPERIDINE

(R)-TERT-BUTYL 3-(AMINOMETHYL)PIPERIDINE-1-CARBOXYLATE

1,1-dimethyl (3R)-3-(aminomethyl)-1-piperidinecarboxylate

tert-Butyl 3-(aminomethyl)piperidine-1-carboxylate

(R)-3-(Aminomethyl)piperidine, N1-BOC protected

(3R)-3-(Aminomethyl)piperidine, N1-BOC protected

(R)-3-Aminomethyl-1-Boc-piperidine

tert-Butyl (3R)-3-(aminomethyl)piperidine-1-carboxylate

(R)-tert-butyl 3-(aMinoMethyl)piperidin-1-carboxylate

3-(Aminomethyl)-1-Boc-piperidine

3-Aminomethyl-piperidine-1-carboxylic acid tert-butyl ester

tert-Butyl (3R)-3-(aminomethyl)piperidine-1-carboxylate, (3R)-3-(Aminomethyl)-1-(tert-butoxycarbonyl)piperidine

tert-butyl (R)-3-(aminomethyl)piperidine-1-carboxylate

(3R)-1-Boc-3-(aminomethyl)piperidine

1-Piperidinecarboxylic acid, 3-(aMinoMethyl)-, 1,1-diMethylethyl ester, (3R)-

(R)-3-Aminomethyl-1-Boc-piperidine,97%

1,1-Dimethylethyl (3R)-3-(aminomethyl)-1-piperidinecarboxylate

CAS:140645-23-4

(R)-1-Boc-3-aminomethyl-piperidine - [A12315]

tert-Butyl (3R)-3-(aminomethyl)-1-piperidinecarboxylate

140645-23-4

Building Blocks

C11

Chemical Synthesis

Heterocyclic Building Blocks

Piperidines