3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE
- Product Name
- 3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE
- CAS No.
- 1268521-33-0
- Chemical Name
- 3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE
- Synonyms
- 4-Bromo-5-chloro-2-nitropyridin-3-amine;3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE;4-Pyridinamine, 3-bromo-2-chloro-5-nitro-
- CBNumber
- CB62567312
- Molecular Formula
- C5H3BrClN3O2
- Formula Weight
- 252.45
- MOL File
- 1268521-33-0.mol
3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE Property
- Boiling point:
- 390.3±37.0 °C(Predicted)
- Density
- 2.020±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- -1.46±0.50(Predicted)
- Appearance
- Off-white to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 2113DV
- Product name
- 3-Bromo-2-chloro-5-nitropyridin-4-amine
- Packaging
- 250mg
- Price
- $253
- Updated
- 2021/12/16
- Product number
- 144373
- Product name
- 3-Bromo-2-chloro-5-nitropyridin-4-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $681
- Updated
- 2021/12/16
- Product number
- 144373
- Product name
- 3-Bromo-2-chloro-5-nitropyridin-4-amine
- Purity
- 95%
- Packaging
- 5g
- Price
- $2043
- Updated
- 2021/12/16
- Product number
- A207058
- Product name
- 3-Bromo-2-chloro-5-nitropyridin-4-amine
- Purity
- 95+%
- Packaging
- 100mg
- Price
- $88
- Updated
- 2021/12/16
- Product number
- A207058
- Product name
- 3-Bromo-2-chloro-5-nitropyridin-4-amine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $151
- Updated
- 2021/12/16
3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE Chemical Properties,Usage,Production
Synthesis
215364-85-5
1268521-33-0
Potassium nitrate (4.87 g, 48.20 mmol) was slowly added to a stirred solution of 3-bromo-2-chloropyridin-4-amine (5.00 g, 24.10 mmol) in concentrated sulfuric acid (36 mL) at about 5 °C. The reaction mixture was gradually warmed to room temperature and stirred continuously for 20 hours. Subsequently, the reaction mixture was slowly poured into crushed ice (~400 mL) and a light yellow precipitate precipitated. The precipitate was collected by filtration and washed with plenty of water. The resulting solid was dried under reduced pressure and added in batches to concentrated sulfuric acid (30 mL), maintaining the temperature at about 5 °C. The reaction mixture was heated to 90 °C and stirred for 2 hours before being cooled to room temperature and allowed to stand for 18 hours. The reaction mixture was again poured into crushed ice (about 400 mL) and a precipitate was precipitated, collected by filtration and washed with cold water. The solid was dissolved in a mixed solvent of methanol and ethyl acetate, and the solution was dried over anhydrous sodium sulfate and concentrated in vacuum to give 3-bromo-2-chloro-5-nitropyridin-4-amine (5.20 g, 85% yield) as a pale orange solid.LCMS (Method I, ESI): retention time = 2.79 min, [M+H]+ = 251.9/253.9/255.9; 1H NMR (400 MHz, DMSO-d6): δ 8.86 (1H, s).
References
[1] Patent: WO2013/7765, 2013, A1. Location in patent: Page/Page column 185-186
3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE manufacturers
- Product
- 3-BROMO-2-CHLORO-5-NITRO-PYRIDIN-4-AMINE 1268521-33-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08