ChemicalBook > CAS DataBase List > 1-(3-Methoxypropyl)-4-piperidinamine

1-(3-Methoxypropyl)-4-piperidinamine

Product Name
1-(3-Methoxypropyl)-4-piperidinamine
CAS No.
179474-79-4
Chemical Name
1-(3-Methoxypropyl)-4-piperidinamine
Synonyms
Prucalopride intermediateB;4-AMino-1-(3-Methoxypropy...;Prucalopride Succinate iMpuritO;3-methoxy propyl piperidinamine;1-(3-methoxypropyl) -4-piperidine;1-(3-Methoxypropyl)-4-piperidimine;1-(3-Methoxypropyl)piperidin-4-aMine;1-(3-Methoxypropyl)-4-piperidinamine;Prucalopride Succinate interMediate B;4-AMino-1-(3-Methoxypropyl)piperidine
CBNumber
CB62589756
Molecular Formula
C9H20N2O
Formula Weight
172.27
MOL File
179474-79-4.mol
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1-(3-Methoxypropyl)-4-piperidinamine Property

Boiling point:
249℃
Density 
0.946
Flash point:
105℃
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Oil
pka
10.49±0.20(Predicted)
color 
Colourless to Pale Yellow
InChI
InChI=1S/C9H20N2O/c1-12-8-2-5-11-6-3-9(10)4-7-11/h9H,2-8,10H2,1H3
InChIKey
HIXAJGFVNMKLML-UHFFFAOYSA-N
SMILES
N1(CCCOC)CCC(N)CC1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific
Product number
Y1133
Product name
1-(3-methoxypropyl)piperidin-4-amine
Packaging
1g
Price
$95
Updated
2021/12/16
AK Scientific
Product number
Y1133
Product name
1-(3-methoxypropyl)piperidin-4-amine
Packaging
10g
Price
$236
Updated
2021/12/16
Matrix Scientific
Product number
115680
Product name
4-Amino-1-(3-methoxypropyl)piperidine
Purity
95+%
Packaging
1g
Price
$572
Updated
2021/12/16
Matrix Scientific
Product number
115680
Product name
4-Amino-1-(3-methoxypropyl)piperidine
Purity
95+%
Packaging
5g
Price
$1580
Updated
2021/12/16
Matrix Scientific
Product number
115680
Product name
4-Amino-1-(3-methoxypropyl)piperidine
Purity
95+%
Packaging
10g
Price
$2222
Updated
2021/12/16
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1-(3-Methoxypropyl)-4-piperidinamine Chemical Properties,Usage,Production

Uses

1-(3-Methoxypropyl)-4-piperidinamine is a useful synthetic intermediate in the synthesis of Prucalopride Succinate (P838950); a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.

Synthesis

N-(1-(3-methoxypropyl)piperidin-4-yl)acetamide (10.72g, 0.05mol) was added to HCl-methanol solution (0.5M, 180ml), and the temperature was controlled at 2025°C After the reaction was detected, it was filtered, and the filter cake was washed with dichloromethane and dried to obtain 1-(3-Methoxypropyl)-4-piperidinamine with a yield of 96.4% and a purity of 99.7%.

1-(3-Methoxypropyl)-4-piperidinamine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(3-Methoxypropyl)-4-piperidinamine Suppliers

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View Lastest Price from 1-(3-Methoxypropyl)-4-piperidinamine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000KG
Release date
2024-07-24
Sach biotech Co.,Ltd
Product
1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
800KGS/month
Release date
2024-07-09
Henan Fengda Chemical Co., Ltd
Product
1-(3-Methoxypropyl)-4-piperidinamine 179474-79-4
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28

179474-79-4, 1-(3-Methoxypropyl)-4-piperidinamineRelated Search:


  • 1-(3-Methoxypropyl)-4-piperidinamine
  • 4-AMino-1-(3-Methoxypropyl)piperidine
  • 4-AMino-1-(3-Methoxypropy...
  • 4-PiperidinaMine, 1-(3-Methoxypropyl)-
  • 1-(3-Methoxypropyl)piperidin-4-aMine
  • Prucalopride Succinate interMediate B
  • Prucalopride intermediateB
  • 1-(3-Methoxypropyl)-4-piperidimine
  • 1-(3-Methoxypropyl)-4-piperidinamine (Plucabili impurity)
  • PRUCALOPRIDE SUCCINATE CAS 179474-85-2 INTERMEDIATES
  • Prucalopride Succinate iMpuritO
  • 3-methoxy propyl piperidinamine
  • 1-(3-methoxypropyl) -4-piperidine
  • 1- (3-methoxypropyl) -4-piperidine amine
  • 179474-79-4
  • 179474-97-4