CAY10650

ChemicalBook > CAS DataBase List > CAY10650

Product Name: CAY10650
CAS No.: 1233706-88-1
Chemical Name: CAY10650
Synonyms: CS-1520;CAY10650;CAY10650, >=98%;CAY 10650;CAY-10650;CAY10650;CAY-10650;CAY 10650;3-isobutanoyl-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]indole-5-carboxylic acid;3-isobutyryl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)-1H-indole-5-carboxylic acid;3-(2-methylpropanoyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid;3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid;1H-Indole-5-carboxylic acid, 3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-
CBNumber: CB62590453
Molecular Formula: C28H25NO6
Formula Weight: 471.5
MOL File: 1233706-88-1.mol

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CAY10650 Property

Melting point:: 103-104℃
Boiling point:: 685.4±55.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml
pka: 4.03±0.30(Predicted)
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10743
Product name: CAY10650
Purity: ≥98%
Packaging: 1mg
Price: $65
Updated: 2024/03/01

Cayman Chemical

Product number: 10743
Product name: CAY10650
Purity: ≥98%
Packaging: 5mg
Price: $286
Updated: 2024/03/01

Cayman Chemical

Product number: 10743
Product name: CAY10650
Purity: ≥98%
Packaging: 10mg
Price: $505
Updated: 2024/03/01

Cayman Chemical

Product number: 10743
Product name: CAY10650
Purity: ≥98%
Packaging: 50mg
Price: $2207
Updated: 2024/03/01

ChemScene

Product number: CS-2024
Product name: CAY10650
Purity: >98.0%
Packaging: 1mg
Price: $60
Updated: 2021/12/16

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CAY10650 Chemical Properties,Usage,Production

Description

Cytosolic phospholipase A2α (cPLA₂α) specifically catalyzes the hydrolysis of arachidonic acid from the sn-2-ester position of membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes, both important mediators of the inflammatory process. CAY10650 is a highly potent (IC₅₀ = 12 nM) cPLA₂α inhibitor. It demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis. The phase I metabolite of this compound, CAY10641 , is also available.

CAY10650 Preparation Products And Raw materials

Raw materials

Preparation Products

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1233706-88-1, CAY10650Related Search:

CAY10650

1H-Indole-5-carboxylic acid, 3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-

3-(2-Methyl-1-oxopropyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid

CAY10650, >=98%

CAY 10650;CAY-10650

CAY10650;CAY-10650;CAY 10650

CS-1520

3-isobutanoyl-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]indole-5-carboxylic acid

3-isobutyryl-1-(2-oxo-3-(4-phenoxyphenoxy)propyl)-1H-indole-5-carboxylic acid

acanthamoeba,inhibit,CAY 10650,PGE2,CAY10650,lipid droplets,neutrophils,keratitis,mannose-induced protein,corneal epithelial cells,CAY-10650,Inhibitor,Phospholipase

3-(2-methylpropanoyl)-1-[2-oxo-3-(4-phenoxyphenoxy)propyl]-1H-indole-5-carboxylic acid

1233706-88-1