3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one
- Product Name
- 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one
- CAS No.
- 799293-83-7
- Chemical Name
- 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one
- Synonyms
- 3-Bromothieno[3,2-c]pyridin-4-ol;3-Bromothieno[3,2-c]pyridin-4(5H);3-BroMothieno[3,2-c]pyridin-4(5H)-one;3-BROMO-4-HYDROXYTHIENO[3,2-C]PYRIDINE;3-Bromo-5H-thieno[3,2-c]pyridine-4-one;Thieno[3,2-c]pyridin-4(5H)-one, 3-bromo-;3-broMo-4-hydroxy-[3,2-c]-thienopyridine;3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one
- CBNumber
- CB62595968
- Molecular Formula
- C7H4BrNOS
- Formula Weight
- 230.08
- MOL File
- 799293-83-7.mol
3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one Property
- Melting point:
- 273-278°C
- Boiling point:
- 468.6±45.0 °C(Predicted)
- Density
- 1.801±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 12.09±0.20(Predicted)
- Appearance
- Light yellow to brown Solid
Safety
- Hazard Codes
- T,C
- Risk Statements
- 25-34-36
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3260 8 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 756237
- Product name
- 3-Bromo-4-hydroxythieno[3,2-c]pyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $97.1
- Updated
- 2023/01/07
- Product number
- B688428
- Product name
- 3-Bromothieno[3,2-c]pyridin-4(5h)-one
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FB143598
- Product name
- 3-Bromothieno[3,2-c]pyridin-4(5H)-one
- Packaging
- 250mg
- Price
- $82.5
- Updated
- 2021/12/16
- Product number
- 8H01-9-01
- Product name
- 3-Bromo-4-hydroxythieno[3,2-c]pyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- FB143598
- Product name
- 3-Bromothieno[3,2-c]pyridin-4(5H)-one
- Packaging
- 500mg
- Price
- $145
- Updated
- 2021/12/16
3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one Chemical Properties,Usage,Production
Synthesis
799293-81-5
799293-83-7
The general procedure for the synthesis of 3-bromo-4-hydroxythienopyridine from the compound (CAS: 799293-81-5) is as follows: 100 mL of diphenyl ether was heated to 210 °C under nitrogen protection, followed by the slow addition of a solution of (E)-3-(4-bromothiophene-2-yl)acryloyl azide (9.95 g, 386 mmol) dissolved in 50 mL of diphenyl ether. The reaction mixture was maintained at 210 °C for 15 min. After completion of the reaction, it was cooled to room temperature and diluted with 100 mL of cyclohexane. The precipitate was collected by filtration and dried under vacuum to give 6.6 g (yield: 74.4%) of the target product 3-bromo-4-hydroxythienopyridine as a brown solid.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 5, p. 1167 - 1171
[2] Patent: US2013/116233, 2013, A1. Location in patent: Paragraph 1153
[3] Patent: US2007/161672, 2007, A1. Location in patent: Page/Page column 8
[4] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 1, p. 250 - 254
[5] Patent: WO2004/100947, 2004, A2. Location in patent: Page 26-27; 17
3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-broMo-4H,5H-thieno[3,2-c]pyridin-4-one manufacturers
- Product
- 3-Bromothieno[3,2-c]pyridin-4(5H)-one 799293-83-7
- Price
- US $2.99/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10KG
- Release date
- 2021-09-24
- Product
- 3-Bromothieno[3,2-c]pyridin-4(5H)-one 799293-83-7
- Price
- US $2.99/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2021-09-24
- Product
- 3-Bromothieno[3,2-c]pyridin-4(5H)-one 799293-83-7
- Price
- US $2.99/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 10kg
- Release date
- 2021-11-26