Heterophyllin B

ChemicalBook > CAS DataBase List > Heterophyllin B

Product Name: Heterophyllin B
CAS No.: 145459-19-4
Chemical Name: Heterophyllin B
Synonyms: Heterophylin B;Heterophyllin B;Prince Ginseng Cyclic Peptide B;Cyclo(glycylglycyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-isoleucyl-L-phenylalanyl);Cyclo(glycylglycyl-L-isoleucyl-L-prolyl-L-prolyl-L-prolyl-L-isole ucyl-L-phenylalanyl);(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone;(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone
CBNumber: CB62604877
Molecular Formula: C40H58N8O8
Formula Weight: 778.94
MOL File: 145459-19-4.mol

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Heterophyllin B Property

Boiling point:: 1159.7±65.0 °C(Predicted)
Density: 1.29±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: 4°C, protect from light
solubility: Soluble in DMSO
pka: 13.44±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 300415
Product name: Heterophyllin B
Packaging: 20mg
Price: $490
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb105560
Product name: Heterophyllin B
Purity: >98%
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

ChemScene

Product number: CS-0016982
Product name: HeterophyllinB
Purity: ≥98.0%
Packaging: 25mg
Price: $640
Updated: 2021/12/16

ChemScene

Product number: CS-0016982
Product name: HeterophyllinB
Purity: ≥98.0%
Packaging: 5mg
Price: $184
Updated: 2021/12/16

ChemScene

Product number: CS-0016982
Product name: HeterophyllinB
Purity: ≥98.0%
Packaging: 10mg
Price: $320
Updated: 2021/12/16

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Heterophyllin B Chemical Properties,Usage,Production

Chemical Properties

White crystal, easily soluble in methanol, derived from Radix Radix.

Uses

Taizishencyclopeptide B has the functions of invigorating qi and blood, invigorating body fluid and invigorating the spleen and stomach. And it was used for content determination/identification/pharmacological experiments, etc.

Biological Activity

Heterophyllin B is an active cyclic peptide isolated from Pseudostellaria heterophylla. It can be used in esophageal cancer research.

in vitro

Heterophyllin B (0-200 μM; 12-48 hours) reduces cell viability in the 75, 100 and 200 μM groups, has no effect on 5, 10, 25 and 50 μM groups.Heterophyllin B (0 -50 μM; 6 hours) suppresses the expression levels of p-PI3K, p-AKT and β-catenin in a dose-dependent manner in ECA-109 cells.

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Cell Viability Assay

Cell Line:	ECA-109 cells
Concentration:	5 μM, 10 μM, 25 μM, 50 μM, 75 μM, 100 μM and 200 μM
Incubation Time:	12, 24 and 48 hours
Result:	Decrease cell viability at high concentrations.

Western Blot Analysis

Cell Line:	ECA-109 cells
Concentration:	0 μM, 10 μM, 25 μM, 50 μM
Incubation Time:	6 hours
Result:	Decreased the phosphorylation of PI3K/AKT and the expression of β-catenin.

Heterophyllin B Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Heterophyllin B manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Heterophyllin B 145459-19-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-12

Career Henan Chemical Co

Product: Heterophyllin B 145459-19-4
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg , 5kg, 50kg
Release date: 2020-01-17

145459-19-4, Heterophyllin BRelated Search:

CARBOXYPEPTIDASE B Chuanxiong segetalin A segetalin B

Heterophyllin B

Heterophylin B

Prince Ginseng Cyclic Peptide B

Cyclo(glycylglycyl-L-isoleucyl-L-prolyl-L-prolyl-L-prolyl-L-isole ucyl-L-phenylalanyl)

Cyclo(glycylglycyl-L-leucyl-L-prolyl-L-prolyl-L-prolyl-L-isoleucyl-L-phenylalanyl)

(6S,15S,18S,20aS,25aS,30aS)-15-Benzyl-18-((S)-sec-butyl)-6-isobutylicosahydro-1H,25H-tripyrrolo[1,2-a:1',2'-d:1'',2''-g][1,4,7,10,13,16,19,22]octaazacyclotetracosin-5,8,11,14,17,20,25,30(30aH)-octaone

145459-19-4

C40H58N8O8

reagent

standard substance