1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro-

Product Name: 1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro-
CAS No.: 1201676-03-0
Chemical Name: 1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro-
Synonyms: 4,6-Dichloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one;4,6-dichloro-1H,2H,3H-pyrrolo[3,4-c]pyridin-1-one;4,6-DICHLORO-2,3-DIHYDROPYRROLO[3,4-C]PYRIDIN-1-ONE;1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro-;4,6-dichloro-2,3-dihydro-1H-pyridinebenzo[3,4-c]pyridine-1-one
CBNumber: CB62607661
Molecular Formula: C7H4Cl2N2O
Formula Weight: 203.03
MOL File: 1201676-03-0.mol

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1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro- Property

Boiling point:: 525.7±50.0 °C(Predicted)
Density: 1.583±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 10.65±0.20(Predicted)
Appearance: Off-white to pink Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

AK Scientific

Product number: 2581AJ
Product name: 4,6-Dichloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one
Packaging: 5g
Price: $3898
Updated: 2021/12/16

Ambeed

Product number: A198498
Product name: 4,6-Dichloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one
Purity: 95%
Packaging: 25mg
Price: $101
Updated: 2021/12/16

Ambeed

Product number: A198498
Product name: 4,6-Dichloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one
Purity: 95%
Packaging: 50mg
Price: $124
Updated: 2021/12/16

J&W Pharmlab

Product number: 69R1070
Product name: 4,6-Dichloro-2,3-dihydro-pyrrolo[3,4-c]pyridin-1-one
Purity: 97%
Packaging: 100mg
Price: $137
Updated: 2021/12/16

Ambeed

Product number: A198498
Product name: 4,6-Dichloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one
Purity: 95%
Packaging: 100mg
Price: $182
Updated: 2021/12/16

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1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro- Chemical Properties,Usage,Production

Synthesis

1201676-02-9

1201676-03-0

General procedure for the synthesis of 4,6-dichloro-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-1-one from ethyl 3-(bromomethyl)-2,6-dichloroisonicotinate: a mixture of ethyl 3-(bromomethyl)-2,6-dichloroisonicotinate (13.4 g, 42.7 mmol), tetrahydrofuran (100 mL) and ammonium hydroxide solution (300 mL, 28- 30% ammonia) was stirred at room temperature for 18 hours. After completion of the reaction, the solvent was removed by rotary evaporator. A small amount of water was added to the almost dry solid, which was separated by filtration to obtain a salmon-colored solid, washed sequentially with a small amount of water and ether, and then dried under vacuum. The filtrate was cooled and filtered to give additional salmon-colored solid (7.47 g, 36.8 mmol, 86% yield). Mass spectrum (ESI) m/z 203.2 (M + 1). 1H NMR (400 MHz, DMSO-d6) δ ppm 9.29 (broad single peak, 1H), 7.83 (single peak, 1H), 4.45 (single peak, 2H).

References

[1] Patent: WO2009/150230, 2009, A1. Location in patent: Page/Page column 180-181
[2] Journal of Medicinal Chemistry, 2010, vol. 53, # 15, p. 5422 - 5438

1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro- Suppliers

China 29 India 1 United States 2 Global 32

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1201676-03-0, 1H-Pyrrolo[3,4-c]pyridin-1-one, 4,6-dichloro-2,3-dihydro-Related Search:

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1201676-03-0