ChemicalBook > CAS DataBase List > 9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one

Product Name
9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
CAS No.
1223002-54-7
Chemical Name
9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
Synonyms
QL-IX-55;QL-IX-55;QL IX 55;QLIX55;9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one;Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]-
CBNumber
CB62614380
Molecular Formula
C24H14F4N4O
Formula Weight
450.3877728
MOL File
1223002-54-7.mol
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9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Property

Boiling point:
640.3±55.0 °C(Predicted)
Density 
1.466
storage temp. 
Store at -20°C
solubility 
DMSO
form 
Powder
pka
5.66±0.26(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Crysdot
Product number
CD31004221
Product name
QL-IX-55
Purity
98+%
Packaging
5mg
Price
$251
Updated
2021/12/16
DC Chemicals
Product number
DC7747
Product name
QL-IX-55
Purity
>98%
Packaging
250mg
Price
$800
Updated
2021/12/16
DC Chemicals
Product number
DC7747
Product name
QL-IX-55
Purity
>98%
Packaging
1g
Price
$1600
Updated
2021/12/16
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9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Chemical Properties,Usage,Production

Uses

QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.

References

[1] Akiyoshi-Shibata M, et al. Further oxidation of hydroxycalcidiol by calcidiol 24-hydroxylase. A study with the mature enzyme expressed in Escherichia coli. Eur J Biochem. 1994 Sep 1;224(2):335-43. DOI:10.1111/j.1432-1033.1994.00335.x

9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one Suppliers

Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
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sales@BioChemBest.com
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China
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6003
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LETOPHARM LIMITED
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+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
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2384
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SPIRO PHARMA
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Fax
-
Email
eric_feng1954@126.com
Country
China
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9248
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Codow Chemical Co.,Ltd.
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18620099427
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+86-20-62619665
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amy@howeipharm.com
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China
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6687
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55
Chengdu Huachun Technology Co., Ltd
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400-1166-196 15982826727
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QQ:800101999
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cdhxsj@163.com
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China
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Jinan Weicheng Pharmaceutical Technology Co., Ltd
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0531-68656072 15562569859
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0531-68656072
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2921569326@qq.com
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China
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Musechem
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+1-800-259-7612
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+1-800-259-7612
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info@musechem.com
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United States
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Jinan Yaoyan Pharmaceutical Co., Ltd.
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Email
jnyaoyan@163.com
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China
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Nanjing Meihao Pharmaceutical Technology Co., Ltd.
Tel
meitaochem@126.com
Email
meitaochem@126.com
Country
China
ProdList
19103
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58
Qi Qi hang Biotechnology Co., Ltd.
Tel
18151111370
Email
1046215251@qq.com
Country
China
ProdList
5999
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View Lastest Price from 9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one manufacturers

Career Henan Chemical Co
Product
9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one 1223002-54-7
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
200g
Release date
2020-02-01

1223002-54-7, 9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-oneRelated Search:


  • QL-IX-55
  • 9-(6-Amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
  • QL-IX-55;QL IX 55;QLIX55
  • Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[4-fluoro-3-(trifluoromethyl)phenyl]-
  • 1223002-54-7
  • C24H14F4N4O