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6-hydroxy-2,3-dihydro-6H-pyrano-3-one

Product Name
6-hydroxy-2,3-dihydro-6H-pyrano-3-one
CAS No.
35436-57-8
Chemical Name
6-hydroxy-2,3-dihydro-6H-pyrano-3-one
Synonyms
2-hydroxy-2H-pyran-5-one;6-Hydroxy-6H-pyran-3-one;6-Hydroxy-2H-pyran-3(6H)-one;2H-Pyran-3(6H)-one, 6-hydroxy-;2-hydroxy-2H-pyran-5-one - [H86570];5,6-Dihydro-2-hydroxy-5-oxo-2H-pyran;2,6-Dihydro-6-hydroxy-3(3H)-pyranone;6-hydroxy-2,3-dihydro-6H-pyrano-3-one
CBNumber
CB62614825
Molecular Formula
C5H6O3
Formula Weight
114.1
MOL File
35436-57-8.mol
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6-hydroxy-2,3-dihydro-6H-pyrano-3-one Property

Melting point:
55-57 °C
Boiling point:
297.8±40.0 °C(Predicted)
Density 
1.353±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
11.47±0.20(Predicted)
Appearance
Off-white to light yellow Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

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N-Bromosuccinimide Price

Crysdot
Product number
CD11137226
Product name
6-Hydroxy-2H-pyran-3(6H)-one
Purity
97%
Packaging
250mg
Price
$49
Updated
2021/12/16
Chemenu
Product number
CM182094
Product name
6-hydroxy-2H-pyran-3(6H)-one
Purity
95+%
Packaging
250mg
Price
$52
Updated
2021/12/16
Crysdot
Product number
CD11137226
Product name
6-Hydroxy-2H-pyran-3(6H)-one
Purity
97%
Packaging
1g
Price
$125
Updated
2021/12/16
Chemenu
Product number
CM182094
Product name
6-hydroxy-2H-pyran-3(6H)-one
Purity
95+%
Packaging
1g
Price
$129
Updated
2021/12/16
Crysdot
Product number
CD11137226
Product name
6-Hydroxy-2H-pyran-3(6H)-one
Purity
97%
Packaging
5g
Price
$374
Updated
2021/12/16
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6-hydroxy-2,3-dihydro-6H-pyrano-3-one Chemical Properties,Usage,Production

Synthesis Reference(s)

Tetrahedron, 27, p. 1973, 1971 DOI: 10.1016/S0040-4020(01)98229-8

Synthesis

98-00-0

35436-57-8

Ten agate grinding balls were filled in an agate mortar, quartz sand (1.50 g), 2-furan methanol (87 μL, 1.0 mmol), and m-chloroperoxybenzoic acid (mCPBA, 345 mg, 2.0 mmol) were added, and the mixture was ground for 30 min. After completion of the reaction, the mixture was diluted with distilled water (15 mL) and filtered. The filtrate was freeze-dried to remove water to afford 6-hydroxy-2H-pyran-3(6H)-one (3a, 108 mg, 95% yield) as a yellow solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ = 6.96 (dd, 1H, J = 3.1,10.4 Hz, 5-H), 6.17 (d, 1H, J = 10.4 Hz, 4-H), 5.64 (d, 1H, J = 3.1 Hz, 6-H), 4.58 (d, 1H, J = 16.9 Hz, 2-H). 4.14 (d, 1H, J = 16.9Hz, 2-H).

References

[1] Heterocycles, 1990, vol. 31, # 11, p. 1941 - 1949
[2] Synthetic Communications, 2015, vol. 45, # 3, p. 348 - 354
[3] Journal of Organic Chemistry, 1997, vol. 62, # 5, p. 1257 - 1263
[4] Organic and Biomolecular Chemistry, 2018, vol. 16, # 31, p. 5566 - 5569
[5] Carbohydrate Research, 1991, vol. 222, p. 163 - 172

6-hydroxy-2,3-dihydro-6H-pyrano-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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6-hydroxy-2,3-dihydro-6H-pyrano-3-one Suppliers

PharmaBlock Sciences (Nanjing),Inc.
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China
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86-21-51320499
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aobo@aobopharm.com
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China
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
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China
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Tianjin Anhao Biological Technology Co., Ltd.
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sales@ahpharmatech.com
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China
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JW & Y Pharmlab Co., Ltd.
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Shanghai YuanYe Biotechnology Co., Ltd.
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ChengDu TongChuangYuan Pharmaceutical Co.Ltd
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028-83379370 13880556291
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028-87747383
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China
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Amadis Chemical Company Limited
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View Lastest Price from 6-hydroxy-2,3-dihydro-6H-pyrano-3-one manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
6-hydroxy-2,3-dihydro-6H-pyrano-3-one 35436-57-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-07-06

35436-57-8, 6-hydroxy-2,3-dihydro-6H-pyrano-3-oneRelated Search:


  • 6-hydroxy-2,3-dihydro-6H-pyrano-3-one
  • 2,6-Dihydro-6-hydroxy-3(3H)-pyranone
  • 5,6-Dihydro-2-hydroxy-5-oxo-2H-pyran
  • 2H-Pyran-3(6H)-one, 6-hydroxy-
  • 6-Hydroxy-2H-pyran-3(6H)-one
  • 6-Hydroxy-6H-pyran-3-one
  • 2-hydroxy-2H-pyran-5-one
  • 2-hydroxy-2H-pyran-5-one - [H86570]
  • 35436-57-8