ChemicalBook > CAS DataBase List > 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate

Product Name
5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
CAS No.
52248-03-0
Chemical Name
5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
Synonyms
VHPOFDUCFKOUHV-XKGORWRGSA-O;S-(5'-Adenosyl)-L-methionine tosylate;S-(5''-Adenosyl)-L-methionine tosylate;P-toluenesulfonic acid adenosylmethionine;P-toluenesulfonic acid adenosylmethionine (SAMe);S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt;S-(5''-Adenosyl)-L-methionine tosylate, 10 mM in DMSO;5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate;5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate;S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt >=80% (HPLC), >=80% (spectrophotometric assay)
CBNumber
CB62616975
Molecular Formula
C22H30N6O8S2
Formula Weight
570.64
MOL File
52248-03-0.mol
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5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Property

Melting point:
78℃
storage temp. 
-20°C
solubility 
DMF: 5 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
A crystalline solid
color 
White to yellow
biological source
synthetic (Organic)
Water Solubility 
H2O: 100mg/mL
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A2408
Product name
S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
Purity
≥80% (HPLC), ≥80% (spectrophotometric assay)
Packaging
25mg
Price
$93.1
Updated
2024/03/01
Sigma-Aldrich
Product number
A2408
Product name
S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
Purity
≥80% (HPLC), ≥80% (spectrophotometric assay)
Packaging
100mg
Price
$190
Updated
2024/03/01
Cayman Chemical
Product number
16376
Product name
S-(5''-Adenosyl)-L-methionine (tosylate)
Packaging
50mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
16376
Product name
S-(5'-Adenosyl)-L-methionine (tosylate)
Packaging
500mg
Price
$632
Updated
2024/03/01
Sigma-Aldrich
Product number
A2408
Product name
S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
Purity
≥80% (HPLC), ≥80% (spectrophotometric assay)
Packaging
500mg
Price
$691
Updated
2024/03/01
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5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Chemical Properties,Usage,Production

Uses

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt has been used for cell proliferation assay. It has also been used for methylation assay.

General Description

S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is used for the treatment of depression, liver cirrhosis, cholestasis and degenerative joint disease.

Biochem/physiol Actions

Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.

5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Preparation Products And Raw materials

Raw materials

Preparation Products

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5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Suppliers

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52248-03-0, 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylateRelated Search:


  • 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
  • ((S)-3-Amino-3-carboxypropyl)(((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(methyl)sulfonium 4-methylbenzenesulfonate
  • VHPOFDUCFKOUHV-XKGORWRGSA-O
  • S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt >=80% (HPLC), >=80% (spectrophotometric assay)
  • P-toluenesulfonic acid adenosylmethionine
  • P-toluenesulfonic acid adenosylmethionine (SAMe)
  • 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
  • S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
  • S-(5'-Adenosyl)-L-methionine tosylate
  • S-(5''-Adenosyl)-L-methionine tosylate
  • S-(5''-Adenosyl)-L-methionine tosylate, 10 mM in DMSO
  • 52248-03-0