ChemicalBook > CAS DataBase List > 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA

1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA

Product Name
1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA
CAS No.
581809-67-8
Chemical Name
1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA
Synonyms
A 425619;A 425619, 10 mM in DMSO;1-(isoquinolin-5-yl)-3-(4-(trifluoromethyl)benzyl)urea;1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA;1-(5-isoquinolinyl)-3-[[4-(trifluoromethyl)phenyl]methyl]urea;N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea;Urea, N-5-isoquinolinyl-N'-[[4-(trifluoromethyl)phenyl]methyl]-
CBNumber
CB62618601
Molecular Formula
C18H14F3N3O
Formula Weight
345.32
MOL File
581809-67-8.mol
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1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
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Safety

HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
42117
Product name
A-425619
Purity
≥98%
Packaging
5mg
Price
$149
Updated
2026/04/30
Cayman Chemical
Product number
42117
Product name
A-425619
Purity
≥98%
Packaging
10mg
Price
$268
Updated
2026/04/30
Cayman Chemical
Product number
42117
Product name
A-425619
Purity
≥98%
Packaging
25mg
Price
$594
Updated
2026/04/30
Cayman Chemical
Product number
42117
Product name
A-425619
Purity
≥98%
Packaging
50mg
Price
$966
Updated
2026/04/30
Tocris
Product number
5781
Product name
A425619
Purity
≥98%(HPLC)
Packaging
10
Price
$210
Updated
2021/12/16
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1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA Chemical Properties,Usage,Production

Uses

A 425619 can be classified as a novel transient receptor potential vanilloid 1 receptor antagonists for the treatment of pain.

in vivo

A-425619 (i.p., 100 μmoL/kg) can restore the reduction of spontaneous digging behavior in C57BL/6J mice induced by complete Freund's adjuvant (CFA; 10 mg/mL) knee joint inflammation[1].

storage

Store at RT

1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA Suppliers

China 28 United Kingdom 1 United States 4 USA 1 Global 34
Nanjing Chemlin Chemical Co., Ltd
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Porse Fine Chemical Co.,LTD
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Hangzhou Molcore Biopharmatech Co.,Ltd
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Shanghai Hongye Biotechnology Co. Ltd
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581809-67-8, 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREARelated Search:


  • 1-(4-(TRIFLUOROMETHYL)BENZYL)-3-(ISOQUINOLIN-5-YL)UREA
  • 1-(isoquinolin-5-yl)-3-(4-(trifluoromethyl)benzyl)urea
  • A 425619
  • N-5-Isoquinolinyl-N'-[[(4-(trifluoromethyl)phenyl]methyl]urea
  • 1-(5-isoquinolinyl)-3-[[4-(trifluoromethyl)phenyl]methyl]urea
  • Urea, N-5-isoquinolinyl-N'-[[4-(trifluoromethyl)phenyl]methyl]-
  • A 425619, 10 mM in DMSO
  • 581809-67-8