JNJ-28312141

Product Name: JNJ-28312141
CAS No.: 885692-52-4
Chemical Name: JNJ-28312141
Synonyms: CS-2012;JNJ-28312141;JNJ-28312141(JNJ-141);JNJ 28312141; JNJ28312141;JNJ-28312141; JNJ28312141; JNJ 28312141.;4-Cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl;4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-{1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL}PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE;1H-Imidazole-2-carboxamide, 5-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]-4-piperidinyl]phenyl]-
CBNumber: CB62621140
Molecular Formula: C26H32N6O2
Formula Weight: 460.57
MOL File: 885692-52-4.mol

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JNJ-28312141 Property

Density: 1.27±0.1 g/cm3(Predicted)
pka: 7.30±0.10(Predicted)
form: White powder.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Adipogen Life Sciences

Product number: SYN-1154-M005
Product name: JNJ-28312141
Purity: ≥95%
Packaging: 5mg
Price: $416
Updated: 2021/12/16

Adipogen Life Sciences

Product number: SYN-1154-M010
Product name: JNJ-28312141
Purity: ≥95%
Packaging: 10mg
Price: $653
Updated: 2021/12/16

AK Scientific

Product number: SYN1154
Product name: JNJ-28312141
Packaging: 10mg
Price: $767.88
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: KIN0001434
Product name: 4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-(1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL)PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE
Purity: 95.00%
Packaging: 1MG
Price: $796.95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: KIN0001434
Product name: 4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-(1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL)PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE
Purity: 95.00%
Packaging: 5MG
Price: $1076.9
Updated: 2021/12/16

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JNJ-28312141 Chemical Properties,Usage,Production

Uses

JNJ-28312141 is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 exhibits anti-inflammatory activity in mouse arthritis model[1].

References

[1] Illig CR, et al., Optimization of a potent class of arylamide colony-stimulating factor-1 receptor inhibitors leading to anti-inflammatory clinical candidate 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141). J Med Chem. 2011 Nov 24;54(22):7860-83. DOI:10.1021/jm200900q

JNJ-28312141 Preparation Products And Raw materials

Raw materials

Preparation Products

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JNJ-28312141 Suppliers

China 37 United Kingdom 1 United States 6 Global 44

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
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Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
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TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 19961
Advantage: 58

Creative Enzymes

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Email: info@creative-enzymes.com
Country: United States
ProdList: 6057
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Matrix Scientific

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Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
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885692-52-4, JNJ-28312141Related Search:

1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol Tariquidar Tofacitinib

CS-2012

JNJ-28312141; JNJ28312141; JNJ 28312141.

JNJ 28312141; JNJ28312141

JNJ-28312141

JNJ-28312141(JNJ-141)

4-Cyano-N-(5-(1-(2-(dimethylamino)acetyl)piperidin-4-yl)-2',3',4',5'-tetrahydro-[1,1'-biphenyl

4-CYANO-N-[2-(CYCLOHEX-1-EN-1-YL)-4-{1-[2-(DIMETHYLAMINO)ACETYL]PIPERIDIN-4-YL}PHENYL]-1H-IMIDAZOLE-2-CARBOXAMIDE

1H-Imidazole-2-carboxamide, 5-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[2-(dimethylamino)acetyl]-4-piperidinyl]phenyl]-

885692-52-4

C26H32N6O2