ChemicalBook > CAS DataBase List > (αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d

(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d

Product Name
(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d
CAS No.
162459-94-1
Chemical Name
(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d
Synonyms
Glycerol phenylbutyrate Impurity 21;7-O-(Triethylsilyl)-2'-O-tert-butyl(diMethyl)silyl-2-debenzoyl Paclitaxel;7-O-(Triethylsilyl)-2′-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel, CAS 162459-94-1;(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d;Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet...
CBNumber
CB62621584
Molecular Formula
C52H75NO13Si2
Formula Weight
978.32
MOL File
162459-94-1.mol
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(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d Property

Boiling point:
905.1±65.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Chloroform, DIchloromethane, Ehtyl Acetate, Methanol
form 
Solid
pka
12.69±0.70(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T777830
Product name
7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl-2-debenzoylPaclitaxel
Packaging
10mg
Price
$165
Updated
2021/12/16
TRC
Product number
T777830
Product name
7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl-2-debenzoylPaclitaxel
Packaging
100mg
Price
$1320
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
53261
Product name
7-O-(Triethylsilyl)-2??-O-tert-butyl(dimethyl)silyl-2-debenzoylPaclitaxel
Packaging
10mg
Price
$650
Updated
2021/12/16
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(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Paclitaxel (P132500) derivative. Intermediate in the preparation of benzoyl-substituted paclitaxel analogs.

(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d Preparation Products And Raw materials

Raw materials

Preparation Products

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(αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d Suppliers

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162459-94-1, (αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dRelated Search:

6,3'-p-dihydroxypaclitaxel Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αR,βR)- 2'-O-Methyl Paclitaxel 7,13-Bis-O-(triethylsilyl) Baccatin III Cabazitaxel Impurity (αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,1 N-[(1,1-dimethylethoxy)carbonyl]Phenylalanine ethyl ester 7-O-(TRIETHYLSILYL) BACCATIN III 3'-P-HYDROXY PACLITAXEL 7-{[(2,2,2,-TRICHLOROETHYL)OXY]CARBONYL} BACCATIN III (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,9,11-trihydroxy-4a,8,13,13-tetramethyl-6-[(triethylsilyl)oxy]-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one (αR,βS)-β-(BenzoylaMino)-α-tert-butyl(diMethyl)silyloxy-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4-triethylsilyloxy-11-hydroxy-4a,8,13,13-tetraMethyl-5-oxo-12-[(1-oxopentyl)oxy]-7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester Paclitaxel Impurity 16 Methyl (2S,3S)-n-benzoyl-3-phenylisoserin hcl cis-cinnamic acid Baccatin V Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, methyl ester, (αS,βR)- 135393-42-9

  • 7-O-(Triethylsilyl)-2'-O-tert-butyl(diMethyl)silyl-2-debenzoyl Paclitaxel
  • (αR,βS)-β-(BenzoylaMino)-α-[[(1,1-diMethylethyl)diMethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-d
  • Benzenepropanoic acid, β-(benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11,12-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet...
  • Glycerol phenylbutyrate Impurity 21
  • 7-O-(Triethylsilyl)-2′-O-tert-butyl(dimethyl)silyl-2-debenzoyl Paclitaxel, CAS 162459-94-1
  • 162459-94-1