4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)-
- Product Name
- 4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)-
- CAS No.
- 326866-17-5
- Chemical Name
- 4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)-
- Synonyms
- FAAH inhibitor 1;Benzothiazole analog 3;FAAH inhibitor 1, 10 mM in DMSO;FAAH inhibitor 1 (Benzothiazole analog 3);4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)-;N-(4-(6-methylbenzo[d]thiazol-2-yl)phenyl)-1-(thiophen-2-ylsulfonyl)piperidine-4-carboxamide;N-(4-(6-Methylbenzo[d]thiazol-2-yl)phenyl)-1-(thiophen-2-ylsulfonyl)piperidine-4-carboxamide , FAAH inhibitor 1;Autophagy,Benzothiazole analog3,inhibit,Fatty acid amide hydrolase,FAAH,FAAH inhibitor1,Benzothiazole analog-3,FAAH inhibitor-1,FAAH inhibitor 1,Inhibitor
- CBNumber
- CB62627081
- Molecular Formula
- C24H23N3O3S3
- Formula Weight
- 497.65272
- MOL File
- 326866-17-5.mol
4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)- Property
- Density
- 1.416±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 13.90±0.70(Predicted)
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- orb611759
- Product name
- FAAH inhibitor 1
- Packaging
- 10mg
- Price
- $438.6
- Updated
- 2021/12/16
- Product number
- orb611759
- Product name
- FAAH inhibitor 1
- Packaging
- 50mg
- Price
- $884
- Updated
- 2021/12/16
- Product number
- orb611759
- Product name
- FAAH inhibitor 1
- Packaging
- 100mg
- Price
- $1516.4
- Updated
- 2021/12/16
- Product number
- CHM0293086
- Product name
- N-[4-(6-METHYL-2-BENZOTHIAZOLYL)PHENYL]-1-(2-THIENYLSULFONYL)-4-PIPERIDINECARBOXAMIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $4966.5
- Updated
- 2021/12/16
- Product number
- CD31002245
- Product name
- FAAHinhibitor1
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $163
- Updated
- 2021/12/16
4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)- Chemical Properties,Usage,Production
Uses
FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM[1].
References
[1] Wang, Xueqing; Sarris, Katerina; Kage, Karen; et al. Synthesis and Evaluation of Benzothiazole-Based Analogues as Novel, Potent, and Selective Fatty Acid Amide Hydrolase Inhibitors. Journal of Medicinal Chemistry (2009), 52(1), 170-180. DOI:10.1021/jm801042a
[2] Meyers, Marvin J.; Long, Scott A.; Pelc, Matthew J.; et al. Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds. Bioorganic & Med DOI:10.1016/j.bmcl.2011.08.055
4-PiperidinecarboxaMide, N-[4-(6-Methyl-2-benzothiazolyl)phenyl]-1-(2-thienylsulfonyl)- Preparation Products And Raw materials
Raw materials
Preparation Products
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