ChemicalBook > CAS DataBase List > 7'-OH-N-trityl Morpholino thyMine

7'-OH-N-trityl Morpholino thyMine

Product Name
7'-OH-N-trityl Morpholino thyMine
CAS No.
914361-76-5
Chemical Name
7'-OH-N-trityl Morpholino thyMine
Synonyms
PMO-T Precusor;Morpholino-5-Me-U;PMO Thymidine Precusor;7'-OH-N-trityl Morpholino thyMine;7-hydroxy-N-trityl morpholinothymidine;7'-Hydroxy-N-tritylmorpholino thymine monomer;1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2, 4(1H, 3H)-dione;1-((2R,6S)-6-(hydroxyMethyl)-4-tritylMorpholin- 2-yl)-5-MethylpyriMidine-2,4-(1H,3H)-dione;1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-
CBNumber
CB62630858
Molecular Formula
C29H29N3O4
Formula Weight
483.56
MOL File
914361-76-5.mol
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7'-OH-N-trityl Morpholino thyMine Property

Density 
1.259±0.06 g/cm3(Predicted)
pka
9.51±0.10(Predicted)
InChIKey
SINOYLIIFJJPCM-IZZNHLLZSA-N
SMILES
C1(=O)N([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C=C(C)C(=O)N1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
NH138533
Product name
7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging
100mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
NH138533
Product name
7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging
250mg
Price
$400
Updated
2021/12/16
Biosynth Carbosynth
Product number
NH138533
Product name
7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging
500mg
Price
$550
Updated
2021/12/16
Biosynth Carbosynth
Product number
NH138533
Product name
7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging
1g
Price
$700
Updated
2021/12/16
Biosynth Carbosynth
Product number
NH138533
Product name
7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging
2g
Price
$1200
Updated
2021/12/16
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7'-OH-N-trityl Morpholino thyMine Chemical Properties,Usage,Production

Description

7'-OH-N-trityl Morpholino thyMine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibiting DNA synthesis, induction of apoptosis, etc.

Uses

7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

7'-OH-N-trityl Morpholino thyMine Preparation Products And Raw materials

Raw materials

Preparation Products

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7'-OH-N-trityl Morpholino thyMine Suppliers

Hongene Biotech Corporation
Tel
021-64757213
Fax
86-21-64700613
Email
info@hongene.com
Country
China
ProdList
672
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Nanjing Baifuli Technology Co., Ltd.
Tel
25-25-58740604 15951658055
Fax
+86-25-58356858
Email
sales@unisyn.cn
Country
China
ProdList
606
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58
Zhengzhou GranLen pharmaceutical Technology Co., Ltd.
Tel
0371-85513397
Email
info@granlen.com
Country
China
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Beijing Qinling Mountains Pharmaceutical Co., Ltd.
Tel
010-61241352 18901327973
Email
834537306@qq.com
Country
China
ProdList
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Tianjin Scaxchem Limited Compnay
Tel
18020011318 18630949181
Email
sales@cosychem.com
Country
China
ProdList
643
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Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
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Jinan Kabotang Biological Technology Co.,Ltd.
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0531-61320525 15866703830
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China
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Fuyang Ziyi Biological Pharmaceutical Co., Ltd.
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19308655899; 19308655899
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Shandong utilizing biological technology co., LTD
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China
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Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.
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19981275275
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914361-76-5, 7'-OH-N-trityl Morpholino thyMineRelated Search:


  • 7'-OH-N-trityl Morpholino thyMine
  • 1-((2R,6S)-6-(hydroxyMethyl)-4-tritylMorpholin- 2-yl)-5-MethylpyriMidine-2,4-(1H,3H)-dione
  • 1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione
  • 7'-Hydroxy-N-tritylmorpholino thymine monomer
  • 1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2, 4(1H, 3H)-dione
  • PMO Thymidine Precusor
  • PMO-T Precusor
  • Morpholino-5-Me-U
  • 2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-
  • 7-hydroxy-N-trityl morpholinothymidine
  • 1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)morpholin-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 914361-76-5