7'-OH-N-trityl Morpholino thyMine
- Product Name
- 7'-OH-N-trityl Morpholino thyMine
- CAS No.
- 914361-76-5
- Chemical Name
- 7'-OH-N-trityl Morpholino thyMine
- Synonyms
- PMO-T Precusor;Morpholino-5-Me-U;PMO Thymidine Precusor;7'-OH-N-trityl Morpholino thyMine;7-hydroxy-N-trityl morpholinothymidine;7'-Hydroxy-N-tritylmorpholino thymine monomer;1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2, 4(1H, 3H)-dione;1-((2R,6S)-6-(hydroxyMethyl)-4-tritylMorpholin- 2-yl)-5-MethylpyriMidine-2,4-(1H,3H)-dione;1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-
- CBNumber
- CB62630858
- Molecular Formula
- C29H29N3O4
- Formula Weight
- 483.56
- MOL File
- 914361-76-5.mol
7'-OH-N-trityl Morpholino thyMine Property
- Density
- 1.259±0.06 g/cm3(Predicted)
- pka
- 9.51±0.10(Predicted)
- InChIKey
- SINOYLIIFJJPCM-IZZNHLLZSA-N
- SMILES
- C1(=O)N([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C=C(C)C(=O)N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- NH138533
- Product name
- 7'-Hydroxy-N-tritylmorpholino thymine monomer
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- NH138533
- Product name
- 7'-Hydroxy-N-tritylmorpholino thymine monomer
- Packaging
- 250mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- NH138533
- Product name
- 7'-Hydroxy-N-tritylmorpholino thymine monomer
- Packaging
- 500mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- NH138533
- Product name
- 7'-Hydroxy-N-tritylmorpholino thymine monomer
- Packaging
- 1g
- Price
- $700
- Updated
- 2021/12/16
- Product number
- NH138533
- Product name
- 7'-Hydroxy-N-tritylmorpholino thymine monomer
- Packaging
- 2g
- Price
- $1200
- Updated
- 2021/12/16
7'-OH-N-trityl Morpholino thyMine Chemical Properties,Usage,Production
Description
7'-OH-N-trityl Morpholino thyMine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibiting DNA synthesis, induction of apoptosis, etc.
Uses
7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
7'-OH-N-trityl Morpholino thyMine Preparation Products And Raw materials
Raw materials
Preparation Products
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