7'-OH-N-trityl Morpholino thyMine

Product Name: 7'-OH-N-trityl Morpholino thyMine
CAS No.: 914361-76-5
Chemical Name: 7'-OH-N-trityl Morpholino thyMine
Synonyms: PMO-T Precusor;Morpholino-5-Me-U;PMO Thymidine Precusor;7'-OH-N-trityl Morpholino thyMine;7-hydroxy-N-trityl morpholinothymidine;7'-Hydroxy-N-tritylmorpholino thymine monomer;1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2, 4(1H, 3H)-dione;1-((2R,6S)-6-(hydroxyMethyl)-4-tritylMorpholin- 2-yl)-5-MethylpyriMidine-2,4-(1H,3H)-dione;1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-
CBNumber: CB62630858
Molecular Formula: C29H29N3O4
Formula Weight: 483.56
MOL File: 914361-76-5.mol

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7'-OH-N-trityl Morpholino thyMine Property

Density: 1.259±0.06 g/cm3(Predicted)
pka: 9.51±0.10(Predicted)
InChIKey: SINOYLIIFJJPCM-IZZNHLLZSA-N
SMILES: C1(=O)N([C@@H]2O[C@H](CO)CN(C(C3=CC=CC=C3)(C3=CC=CC=C3)C3=CC=CC=C3)C2)C=C(C)C(=O)N1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: NH138533
Product name: 7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging: 100mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NH138533
Product name: 7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging: 250mg
Price: $400
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NH138533
Product name: 7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging: 500mg
Price: $550
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NH138533
Product name: 7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging: 1g
Price: $700
Updated: 2021/12/16

Biosynth Carbosynth

Product number: NH138533
Product name: 7'-Hydroxy-N-tritylmorpholino thymine monomer
Packaging: 2g
Price: $1200
Updated: 2021/12/16

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7'-OH-N-trityl Morpholino thyMine Chemical Properties,Usage,Production

Description

7'-OH-N-trityl Morpholino thyMine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibiting DNA synthesis, induction of apoptosis, etc.

Uses

7’-OH-N-trityl morpholinothymine (PMO Thymidine Precusor) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

7'-OH-N-trityl Morpholino thyMine Preparation Products And Raw materials

Raw materials

Preparation Products

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7'-OH-N-trityl Morpholino thyMine Suppliers

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914361-76-5, 7'-OH-N-trityl Morpholino thyMineRelated Search:

7'-OH-N-trityl Morpholino thyMine

1-((2R,6S)-6-(hydroxyMethyl)-4-tritylMorpholin- 2-yl)-5-MethylpyriMidine-2,4-(1H,3H)-dione

1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

7'-Hydroxy-N-tritylmorpholino thymine monomer

1-(6-(hydroxymethyl)-4-tritylmorpholin-2-yl)-5-methylpyrimidine-2, 4(1H, 3H)-dione

PMO Thymidine Precusor

PMO-T Precusor

Morpholino-5-Me-U

2,4(1H,3H)-Pyrimidinedione, 1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-

7-hydroxy-N-trityl morpholinothymidine

1-[(2R,6S)-6-(hydroxymethyl)-4-(triphenylmethyl)morpholin-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

914361-76-5