3-cyclopropyl-2-fluoropyridine

Product Name: 3-cyclopropyl-2-fluoropyridine
CAS No.: 1227177-68-5
Chemical Name: 3-cyclopropyl-2-fluoropyridine
Synonyms: 3-cyclopropyl-2-fluoropyridine;Pyridine, 3-cyclopropyl-2-fluoro-
CBNumber: CB62631299
Molecular Formula: C8H8FN
Formula Weight: 137.15
MOL File: 1227177-68-5.mol

More

Less

3-cyclopropyl-2-fluoropyridine Property

Boiling point:: 187.1±28.0 °C(Predicted)
Density: 1.194±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: -0.06±0.10(Predicted)
Appearance: Colorless to light yellow Liquid

More

Less

Safety

HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: C991975
Product name: 3-Cyclopropyl-2-fluoropyridine
Packaging: 100mg
Price: $255
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-3-0R
Product name: 3-Cyclopropyl-2-fluoropyridine
Purity: 97%
Packaging: 250mg
Price: $309
Updated: 2021/12/16

AK Scientific

Product number: Y3884
Product name: 3-Cyclopropyl-2-fluoropyridine
Packaging: 250mg
Price: $321
Updated: 2021/12/16

Apolloscientific

Product number: PC201078
Product name: 3-Cyclopropyl-2-fluoropyridine
Purity: 97%
Packaging: 100mg
Price: $121
Updated: 2021/12/16

Apolloscientific

Product number: PC201078
Product name: 3-Cyclopropyl-2-fluoropyridine
Purity: 97%
Packaging: 250mg
Price: $193
Updated: 2021/12/16

More

Less

3-cyclopropyl-2-fluoropyridine Chemical Properties,Usage,Production

Synthesis

1065010-87-8

113975-22-7

1227177-68-5

2-Fluoro-3-iodopyridine (300 mg, 1.34 mmol), potassium cyclopropyltrifluoroborate (498 mg, 3.36 mmol) and palladium(II) acetate (30 mg, 0.135 mmol) were dissolved in toluene (4 mL) under nitrogen protection. Tricyclohexylphosphine (75 mg, 0.27 mmol), tripotassium phosphate (1.1 g, 5.38 mmol) and water (0.4 mL) were then added. The reaction mixture was placed in a microwave reactor and heated at 130 °C for 2 hours. After completion of the reaction, it was cooled to room temperature, water was added and the aqueous layer was extracted with dichloromethane (DCM). The organic layers were combined, washed sequentially with water and brine, dried over anhydrous sodium sulfate, and concentrated to give 3-cyclopropyl-2-fluoropyridine (200 mg, 97% yield). UPLC-MS (Method 2): retention time (R) = 0.94 min; MS (ESI positive ion mode): m/z = 138 ([M + H]+).

References

[1] Patent: WO2014/184275, 2014, A1. Location in patent: Page/Page column 107; 108
[2] Patent: US2014/343065, 2014, A1. Location in patent: Paragraph 0449; 0450; 0451

3-cyclopropyl-2-fluoropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

3-cyclopropyl-2-fluoropyridine Suppliers

China 23 India 2 United States 5 Global 30

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7891
Advantage: 64

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39999
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

AAB-PHARMA LIMITED

Tel: 025-66800956 18800000000
Fax: qq3325708371
Email: sales@njdmchem.com
Country: China
ProdList: 4200
Advantage: 50

Jinan Weicheng Pharmaceutical Technology Co., Ltd

Tel: 0531-68656072 15562569859
Fax: 0531-68656072
Email: 2921569326@qq.com
Country: China
ProdList: 57
Advantage: 55

Aikon International Limited

Tel: 025-58859352 19370895928
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15491
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3290
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 021-4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52678
Advantage: 58

Shanghai Scochem Technology Co., Ltd.

Tel: 021-33758897 15801866362;
Email: sales@scochem.com
Country: China
ProdList: 1596
Advantage: 58

Shanghai Lanle Bird Industrial Co., Ltd.

Tel: 15021845385
Email: 765325601@qq.com
Country: China
ProdList: 3609
Advantage: 58

More

Less

View Lastest Price from 3-cyclopropyl-2-fluoropyridine manufacturers

Career Henan Chemical Co

Product: 3-cyclopropyl-2-fluoropyridine 1227177-68-5
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200g
Release date: 2020-02-01

1227177-68-5, 3-cyclopropyl-2-fluoropyridineRelated Search:

3-cyclopropyl-2-fluoropyridine

Pyridine, 3-cyclopropyl-2-fluoro-

1227177-68-5