ChemicalBook > CAS DataBase List > 4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester

4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester

Product Name: 4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester
CAS No.: 39497-01-3
Chemical Name: 4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester
Synonyms: 2-hydroxy-4-carbomethoxyquinoline;Methyl 2-Oxo-1H-quinoline-4-carboxylate;Methyl 2-oxo-1,2-dihydroquinoline-4-carboxylate;4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester;Methyl 2-oxo-1,2-dihydroquinoline-4-carboxylate, 97%, QE-2343
CBNumber: CB62639361
Molecular Formula: C11H9NO3
Formula Weight: 203.19
MOL File: 39497-01-3.mol

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4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Property

storage temp.: Inert atmosphere,Room Temperature
Appearance: White to light brown Solid
InChI: InChI=1S/C11H9NO3/c1-15-11(14)8-6-10(13)12-9-5-3-2-4-7(8)9/h2-6H,1H3,(H,12,13)
InChIKey: VVZNRIXRLYHAKG-UHFFFAOYSA-N
SMILES: N1C2=C(C=CC=C2)C(C(OC)=O)=CC1=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: B496065
Product name: Methyl2-Oxo-1H-quinoline-4-carboxylate
Packaging: 50mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: CS-0039009
Product name: Methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
Packaging: 5g
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: CS-0039009
Product name: Methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
Packaging: 10g
Price: $116
Updated: 2021/12/16

Chemenu

Product number: CM143081
Product name: methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
Purity: 95%
Packaging: 10g
Price: $143
Updated: 2021/12/16

Chemenu

Product number: CM143081
Product name: methyl2-oxo-1,2-dihydroquinoline-4-carboxylate
Purity: 95%
Packaging: 25g
Price: $262
Updated: 2021/12/16

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4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Chemical Properties,Usage,Production

Synthesis

67-56-1

15733-89-8

39497-01-3

Example II Synthesis of 2-quinoline triazole derivatives: 2-hydroxyquinoline-4-carboxylic acid (500 mg, 2.65 mmol) was suspended in anhydrous methanol and concentrated sulfuric acid (96%, 40 drops) was added slowly. The reaction mixture was heated to reflux until the solution became clear. Stirring was continued under reflux conditions for 18 hours (the reaction was monitored by LC-MS until the starting material disappeared completely). Upon completion of the reaction, it was cooled to room temperature and a white precipitate was precipitated. The precipitate was collected by filtration and washed with diethyl ether to give a white solid product in 70% yield (0.38 g). The product was characterized by 1H NMR (DMSO, INOVA-400): δ 3.91 (s, 3H), 6.88 (d, 1H, J = 1.6 Hz), 7.22 (td, 1H, Jt = 7.5 Hz, 0.8 Hz), 7.35 (d, 1H, J = 8.4 Hz), 7.55 (td, 1H, Jt = 7.2 Hz).

References

[1] Patent: WO2012/6068, 2012, A2. Location in patent: Page/Page column 64-65
[2] Patent: WO2006/66584, 2006, A1. Location in patent: Page/Page column 19
[3] Chemistry - A European Journal, 2009, vol. 15, # 24, p. 5950 - 5955
[4] Patent: WO2007/9250, 2007, A1. Location in patent: Page/Page column 40

4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl ester Suppliers

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39497-01-3, 4-Quinolinecarboxylic acid, 1,2-dihydro-2-oxo-, Methyl esterRelated Search:

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39497-01-3