1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride
- Product Name
- 1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride
- CAS No.
- 126055-32-1
- Chemical Name
- 1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride
- Synonyms
- -4-methylpiperazine hydrochloride;(2E)-3-(5-methyl-54-furyl)acrylic acid;1-(2-Chloroethyl)-4-methylpiperazine HCl;1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride;Piperazine, 1-(2-chloroethyl)-4-methyl-, hydrochloride (1:1)
- CBNumber
- CB62645179
- Molecular Formula
- C7H16Cl2N2
- Formula Weight
- 199.12134
- MOL File
- 126055-32-1.mol
1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride Property
- Melting point:
- 279-280 °C (decomp)
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933599590
N-Bromosuccinimide Price
- Product number
- C984658
- Product name
- 1-(2-Chloroethyl)-4-methylpiperazineHydrochloride
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR930991
- Product name
- 1-(2-Chloroethyl)-4-methylpiperazinehydrochloride
- Purity
- 95%
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- 3H32-5-NJ
- Product name
- 1-(2-Chloroethyl)-4-methylpiperazinehydrochloride
- Purity
- 95%
- Packaging
- 1g
- Price
- $184
- Updated
- 2021/12/16
- Product number
- OR930991
- Product name
- 1-(2-Chloroethyl)-4-methylpiperazinehydrochloride
- Purity
- 95%
- Packaging
- 5g
- Price
- $345
- Updated
- 2021/12/16
- Product number
- HCH0361776
- Product name
- 1-(2-CHLOROETHYL)-4-METHYLPIPERAZINE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.99
- Updated
- 2021/12/16
1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride Chemical Properties,Usage,Production
Synthesis
109-01-3
107-04-0
5753-26-4
1. 10 mL of 25% NaOH solution and 1 mL (9 mmol) of N-methylpiperazine were added sequentially to the reaction flask. 2. the mixture was heated to 50 °C and 1.8 mL (18 mmol) of 1-bromo-2-chloroethane was added slowly and dropwise. 3. The reaction mixture was kept at 50 °C with stirring for 6 hours and subsequently cooled to room temperature. 4. The reaction solution was extracted using ethyl acetate, the extract was washed with saturated brine solution, dried over anhydrous sodium sulfate and filtered. 5. The filtrate was concentrated to dryness under reduced pressure and a small amount of ethanol/NaOH solution was added dropwise to the residue. 6. The mixture was shaken and allowed to stand in a refrigerator and subsequently concentrated to dryness under reduced pressure to give 0.43 g of the white solid product 1-(2-chloroethyl)-4-methylpiperazine dihydrochloride in 23% yield. 7. The melting point of the product was determined to be 227-230 °C.
References
[1] Patent: US2013/85140, 2013, A1. Location in patent: Paragraph 0064; 0065
1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
1-(2-Chloroethyl)-4-Methylpiperazine hydrochloride Suppliers
- Tel
- 513-85982855 18921614129
- Fax
- 051385915507
- sales@xianxingpharm.com
- Country
- China
- ProdList
- 2986
- Advantage
- 61
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 028-84252981
- Fax
- +86-28-84252965
- sales@chembon.com.cn
- Country
- China
- ProdList
- 850
- Advantage
- 64
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- 15026594951
- Fax
- 0556-5030632
- rs@raise-chem.com
- Country
- China
- ProdList
- 4454
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 20-66003216 18666003216
- Fax
- +86-20-28069063
- info@porsefinechemical.com
- Country
- China
- ProdList
- 1941
- Advantage
- 62
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 13764913901
- Fax
- -
- info@angtibio.com
- Country
- China
- ProdList
- 4985
- Advantage
- 55