5-(trifluoroMethyl)pyrazine-2-carboxylic acid

Product Name: 5-(trifluoroMethyl)pyrazine-2-carboxylic acid
CAS No.: 1174321-06-2
Chemical Name: 5-(trifluoroMethyl)pyrazine-2-carboxylic acid
Synonyms: 180624;5-Difluoromethylpyrazine-2-carboxylic acid;5-(Difluoromethyl)-2-pyrazinecarboxylic acid;5-(trifluoroMethyl)pyrazine-2-carboxylic acid;2-Pyrazinecarboxylic acid, 5-(difluoromethyl)-
CBNumber: CB62654180
Molecular Formula: C6H4F2N2O2
Formula Weight: 174.1
MOL File: 1174321-06-2.mol

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5-(trifluoroMethyl)pyrazine-2-carboxylic acid Property

Boiling point:: 319.8±42.0 °C(Predicted)
Density: 1.496±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 2.59±0.10(Predicted)
Appearance: Light yellow to yellow Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D452643
Product name: 5-(Difluoromethyl)pyrazine-2-carboxylicAcid
Packaging: 10mg
Price: $60
Updated: 2021/12/16

TRC

Product number: D452643
Product name: 5-(Difluoromethyl)pyrazine-2-carboxylicAcid
Packaging: 50mg
Price: $130
Updated: 2021/12/16

AK Scientific

Product number: 5628DN
Product name: 5-(Difluoromethyl)pyrazine-2-carboxylicacid
Packaging: 100mg
Price: $87
Updated: 2021/12/16

Apolloscientific

Product number: PC520751
Product name: 5-(Difluoromethyl)pyrazine-2-carboxylicacid
Purity: 95%
Packaging: 1g
Price: $126
Updated: 2021/12/16

Matrix Scientific

Product number: 087163
Product name: 5-(Difluoromethyl)pyrazine-2-carboxylic acid
Purity: 95%
Packaging: 500mg
Price: $285
Updated: 2021/12/16

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5-(trifluoroMethyl)pyrazine-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

1174321-09-5

1174321-06-2

A3-5 (1.5 g, 6.5 mmol) was dissolved in dichloromethane (DCM, 20 mL) at 0 °C and trifluoroacetic acid (TFA, 2 mL) was added slowly and dropwise. The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford the product A3-6 (1 g, 88% yield). The structure of the product was confirmed by 1H NMR (400 MHz, MeOD): δ 9.30 (s, 1H), 8.98 (s, 1H), 6.92 (t, J = 14.4 Hz, 1H).

References

[1] Patent: WO2012/138734, 2012, A1. Location in patent: Page/Page column 65-66
[2] Patent: US2009/209755, 2009, A1. Location in patent: Page/Page column 54-55
[3] Patent: US2010/93999, 2010, A1. Location in patent: Page/Page column 49
[4] Patent: WO2011/9897, 2011, A1. Location in patent: Page/Page column 74; 76
[5] Patent: WO2011/9898, 2011, A1. Location in patent: Page/Page column 86; 87

5-(trifluoroMethyl)pyrazine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(trifluoroMethyl)pyrazine-2-carboxylic acid Suppliers

China 67 France 1 India 1 United States 6 Global 75

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View Lastest Price from 5-(trifluoroMethyl)pyrazine-2-carboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-(Difluoromethyl)-2-pyrazinecarboxylic acid 1174321-06-2
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-17

Qingdao RENAS Polymer Material Co., Ltd.

Product: Koch acid;8-aminonaphthalene-1,3,6-trisulphonic acid 1174321-06-2
Price: US $0.00/kg
Min. Order: 20kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-10-10

Qingdao RENAS Polymer Material Co., Ltd.

Product: 5-(difluoromethyl)pyrazine-2-carboxylic acid 1174321-06-2
Price: US $0.00/kg
Min. Order: 20kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-10-10

1174321-06-2, 5-(trifluoroMethyl)pyrazine-2-carboxylic acidRelated Search:

180624

5-(trifluoroMethyl)pyrazine-2-carboxylic acid

5-Difluoromethylpyrazine-2-carboxylic acid

2-Pyrazinecarboxylic acid, 5-(difluoromethyl)-

5-(Difluoromethyl)-2-pyrazinecarboxylic acid

1174321-06-2