5-(trifluoroMethyl)pyrazine-2-carboxylic acid
- Product Name
- 5-(trifluoroMethyl)pyrazine-2-carboxylic acid
- CAS No.
- 1174321-06-2
- Chemical Name
- 5-(trifluoroMethyl)pyrazine-2-carboxylic acid
- Synonyms
- 180624;5-Difluoromethylpyrazine-2-carboxylic acid;5-(Difluoromethyl)-2-pyrazinecarboxylic acid;5-(trifluoroMethyl)pyrazine-2-carboxylic acid;2-Pyrazinecarboxylic acid, 5-(difluoromethyl)-
- CBNumber
- CB62654180
- Molecular Formula
- C6H4F2N2O2
- Formula Weight
- 174.1
- MOL File
- 1174321-06-2.mol
5-(trifluoroMethyl)pyrazine-2-carboxylic acid Property
- Boiling point:
- 319.8±42.0 °C(Predicted)
- Density
- 1.496±0.06 g/cm3 (20 ºC 760 Torr)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 2.59±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H318Causes serious eye damage
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D452643
- Product name
- 5-(Difluoromethyl)pyrazine-2-carboxylicAcid
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- D452643
- Product name
- 5-(Difluoromethyl)pyrazine-2-carboxylicAcid
- Packaging
- 50mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- PC520751
- Product name
- 5-(Difluoromethyl)pyrazine-2-carboxylicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $126
- Updated
- 2021/12/16
- Product number
- 087163
- Product name
- 5-(Difluoromethyl)pyrazine-2-carboxylic acid
- Purity
- 95%
- Packaging
- 500mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- PC520751
- Product name
- 5-(Difluoromethyl)pyrazine-2-carboxylicacid
- Purity
- 95%
- Packaging
- 5g
- Price
- $348
- Updated
- 2021/12/16
5-(trifluoroMethyl)pyrazine-2-carboxylic acid Chemical Properties,Usage,Production
Synthesis
1174321-09-5
1174321-06-2
A3-5 (1.5 g, 6.5 mmol) was dissolved in dichloromethane (DCM, 20 mL) at 0 °C and trifluoroacetic acid (TFA, 2 mL) was added slowly and dropwise. The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure to afford the product A3-6 (1 g, 88% yield). The structure of the product was confirmed by 1H NMR (400 MHz, MeOD): δ 9.30 (s, 1H), 8.98 (s, 1H), 6.92 (t, J = 14.4 Hz, 1H).
References
[1] Patent: WO2012/138734, 2012, A1. Location in patent: Page/Page column 65-66
[2] Patent: US2009/209755, 2009, A1. Location in patent: Page/Page column 54-55
[3] Patent: US2010/93999, 2010, A1. Location in patent: Page/Page column 49
[4] Patent: WO2011/9897, 2011, A1. Location in patent: Page/Page column 74; 76
[5] Patent: WO2011/9898, 2011, A1. Location in patent: Page/Page column 86; 87
5-(trifluoroMethyl)pyrazine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-(trifluoroMethyl)pyrazine-2-carboxylic acid manufacturers
- Product
- 5-(Difluoromethyl)-2-pyrazinecarboxylic acid 1174321-06-2
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-17
- Product
- Koch acid;8-aminonaphthalene-1,3,6-trisulphonic acid 1174321-06-2
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-10-10
- Product
- 5-(difluoromethyl)pyrazine-2-carboxylic acid 1174321-06-2
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-10-10