N-Methyl-N-isopropylsulfamoyl amide
- Product Name
- N-Methyl-N-isopropylsulfamoyl amide
- CAS No.
- 372136-76-0
- Chemical Name
- N-Methyl-N-isopropylsulfamoyl amide
- Synonyms
- METHYL ISO PROPYL SULFAMIDE;N-isopropyl-N-methylsulfamide;N-Methyl-N-isopropylsulfamide;2-[methyl(sulfamoyl)amino]propane;N-Methyl-N-isopropylsulfamoyl amide;[METHYL(PROPAN-2-YL)SULFAMOYL]AMINE;N-Methyl-N-(1-methylethyl)sulfamide;SulfaMide, N-Methyl-N-(1-Methylethyl)-;N-methyl-N-(1-methylethyl)aminosulfonamide
- CBNumber
- CB62659701
- Molecular Formula
- C4H12N2O2S
- Formula Weight
- 152.22
- MOL File
- 372136-76-0.mol
N-Methyl-N-isopropylsulfamoyl amide Property
- Boiling point:
- 238.7±23.0 °C(Predicted)
- Density
- 1.199±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Acetone; Dichloromethane; Methanol
- pka
- 12.40±0.60(Predicted)
- form
- Solid
- color
- White
- InChI
- InChI=1S/C4H12N2O2S/c1-4(2)6(3)9(5,7)8/h4H,1-3H3,(H2,5,7,8)
- InChIKey
- PJNPCKSPJXQBHH-UHFFFAOYSA-N
- SMILES
- S(N(C)C(C)C)(N)(=O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- I872708
- Product name
- N-Isopropyl-N-methylsulfamide
- Packaging
- 500mg
- Price
- $610
- Updated
- 2021/12/16
- Product number
- AS147134
- Product name
- N-Methyl-N-isopropylsulfamoylamide
- Purity
- 95%
- Packaging
- 5G
- Price
- $553
- Updated
- 2021/12/16
- Product number
- 3943DA
- Product name
- [Methyl(propan-2-yl)sulfamoyl]amine
- Packaging
- 10g
- Price
- $2665
- Updated
- 2021/12/16
- Product number
- CD13014420
- Product name
- N-Methyl-N-isopropylsulfamoylamide
- Purity
- 95+%
- Packaging
- 5g
- Price
- $780
- Updated
- 2021/12/16
- Product number
- A841146
- Product name
- N-Methyl-N-isopropylsulfamoylamide
- Purity
- 95%
- Packaging
- 100mg
- Price
- $29
- Updated
- 2021/12/16
N-Methyl-N-isopropylsulfamoyl amide Chemical Properties,Usage,Production
Uses
N-Isopropyl-N-methylsulfamide is an intermediate in the synthesis of unlabeled Saflufenacil-d7 (S081802). Saflufenacil-d7 is the labeled version of Saflufenacil (S081800), which is a herbicide of the pyrimidinedione chemical class used for the preplant burndown and selective preemergence dicot weed control in different field crops. It was found to inhibit protoporphyrinogen IX oxidase (PPO) enzyme.
Synthesis
Add 160g of ethanol to a 500ml four-necked flask, stir and cool to -5℃. Then, pass 18g (1.06mol) of ammonia gas, control the temperature at -5~0℃ and add 40g (0.23mol) of N-methyl-N-isopropylaminosulfonyl chloride at 0℃. After the addition is completed, keep warm for 1 hour, then control the vacuum of the reaction solution to -0.07MPa, the water bath temperature to 40℃, and concentrate under reduced pressure to dry solid. Add the solid to 120g of dichloromethane, stir at room temperature for 30 minutes to dissolve, and filter to obtain the filtrate. The filtrate is concentrated to dryness under reduced pressure at -0.07MPa and water bath temperature at 40℃ to obtain 33.7g of the product N-Methyl-N-isopropylsulfamoyl amide (HPLC purity 98.2%, yield 95%).
N-Methyl-N-isopropylsulfamoyl amide Preparation Products And Raw materials
Raw materials
Preparation Products
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