ChemicalBook > CAS DataBase List > H-TYR-TYR-OH

H-TYR-TYR-OH

Product Name
H-TYR-TYR-OH
CAS No.
1050-28-8
Chemical Name
H-TYR-TYR-OH
Synonyms
TYR-TYR;H-TYR-TYR-OH;tyrosyltyrosine;H-Tyr-Tyr-OH Hcl;TYR-TYR CRYSTALLINE;L-TYROSYL-L-TYROSINE;L-Tyrosine, L-tyrosyl-;Peptide tyrosine-tyrosine;(S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-3-(4-hydroxyphenyl)propanoic acid;(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propionic acid
CBNumber
CB6266161
Molecular Formula
C18H20N2O5
Formula Weight
344.36
MOL File
1050-28-8.mol
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H-TYR-TYR-OH Property

Melting point:
300 °C (decomp)
Boiling point:
703.1±60.0 °C(Predicted)
Density 
1.372±0.06 g/cm3(Predicted)
storage temp. 
-15°C
pka
pK1:3.52(+1);pK2:7.68(0);pK3:9.80(+1);pK4:10.26(+2) (25°C)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T966390
Product name
H-Tyr-Tyr-OH
Packaging
50mg
Price
$130
Updated
2021/12/16
Chem-Impex
Product number
06259
Product name
H-Tyr-Tyr-OH
Packaging
100MG
Price
$559.1
Updated
2021/12/16
Chem-Impex
Product number
06259
Product name
H-Tyr-Tyr-OH
Packaging
5MG
Price
$745.47
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006994
Product name
L-TYROSYL-L-TYROSINE
Purity
98.00%
Packaging
1G
Price
$1131.9
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0006994
Product name
L-TYROSYL-L-TYROSINE
Purity
98.00%
Packaging
5G
Price
$1409.1
Updated
2021/12/16
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H-TYR-TYR-OH Chemical Properties,Usage,Production

Uses

H-TYR-TYR-OH (cas# 1050-28-8) is an antihypertensive peptide with angiotensin I-converting enzyme (ACE) inhibitory activity prepared from the powder of the jellyfish.

Definition

ChEBI: Tyrosyltyrosine in which each tyrosine residue has L-configuration.

in vivo

H-Tyr-Tyr-OH (12.5 mg/kg; intraarterial injection once) effects systolic blood pressure in vivo[1]. H-Tyr-Tyr-OH (0-100 mg/kg; i.p. once) effects blood pressure of spontaneously hypertensive rats[1].

Animal Model:Anesthetized male SpragueDawley rats[1]
Dosage:12.5 mg/kg
Administration:Intraarterial injection; 12.5 mg/kg once
Result:Significantly elevated systolic blood pressure, with a peak increase of 5 min after administration.
Animal Model:Spontaneously hypertensive rats[1]
Dosage:0, 50 and 100 mg/kg
Administration:Intraperitoneal injection; once
Result:Significantly reduced blood pressure of spontaneously hypertensive rats, even at a dose of 50 mg/kg.

H-TYR-TYR-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-TYR-TYR-OH Suppliers

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View Lastest Price from H-TYR-TYR-OH manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
H-TYR-TYR-OH 1050-28-8
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-07-07

1050-28-8, H-TYR-TYR-OHRelated Search:


  • tyrosyltyrosine
  • H-TYR-TYR-OH
  • TYR-TYR
  • TYR-TYR CRYSTALLINE
  • (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • (2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propionic acid
  • (2S)-2-[[(2S)-2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
  • L-TYROSYL-L-TYROSINE
  • L-Tyrosine, L-tyrosyl-
  • Peptide tyrosine-tyrosine
  • (S)-2-((S)-2-Amino-3-(4-hydroxyphenyl)propanamido)-3-(4-hydroxyphenyl)propanoic acid
  • H-Tyr-Tyr-OH Hcl
  • 1050-28-8
  • C18H20N2O5