N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib

Product Name: N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib
CAS No.: 186392-65-4
Chemical Name: N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib
Synonyms: 296;CP296;CP-296;CP 296;CPD2802;GPi 296;CP368296;CP-368296;CP 368296;Ingliforib
CBNumber: CB62663621
Molecular Formula: C23H24ClN3O5
Formula Weight: 457.91
MOL File: 186392-65-4.mol

More

Less

N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib Property

Melting point:: 238 °C
Boiling point:: 843.3±65.0 °C(Predicted)
Density: 1.495±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:130.0(Max Conc. mg/mL);283.9(Max Conc. mM)
form: Solid
pka: 12.88±0.20(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb611953
Product name: Ingliforib
Purity: >98%
Packaging: 100mg
Price: $1431.4
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611953
Product name: Ingliforib
Purity: >98%
Packaging: 250mg
Price: $2691.1
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611953
Product name: Ingliforib
Purity: >98%
Packaging: 1g
Price: $5358.4
Updated: 2021/12/16

DC Chemicals

Product number: DC26023
Product name: Ingliforib
Purity: >98%
Packaging: 100mg
Price: $950
Updated: 2021/12/16

DC Chemicals

Product number: DC26023
Product name: Ingliforib
Purity: >98%
Packaging: 1g
Price: $3600
Updated: 2021/12/16

More

Less

N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib Chemical Properties,Usage,Production

Uses

Treatment of type 2 diabetes mellitus (glycogen phosphorylase inhibitor).

Definition

ChEBI: Ingliforib is an indolecarboxamide.

in vivo

Ingliforib (15 mg/kg) potently reduces infarct size by 52%, and decreases plasma glucose and lactate concentrations in openchest anesthetized rabbits. Ingliforib (15 mg/kg) also inhibits myocardial glycogen phosphorylase a (GPa) and total glycogen phosphorylase (GP) activity in anesthetized rabbits^[1].

N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib Suppliers

China 49 United States 4 Global 53

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3506
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4757
Advantage: 55

Guangzhou Zhiya Chemdrugs Co.,Ltd

Tel: 18122150900
Fax: QQ:2869377561
Email: sculk28@163.com
Country: China
ProdList: 646
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1944
Advantage: 55

Shanghai Tube Pharmaceutical Co., Ltd.

Tel: 021-54338626 18017892860
Fax: 021-54338626
Email: sales@tubepharm.com
Country: China
ProdList: 2572
Advantage: 58

186392-65-4, N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforibRelated Search:

N-{(1S,2R)-1-benzyl-3-[(3R,4S)-3,4-dihydroxypyrrolidin-1-yl]-2-hydroxy-3-oxopropyl}-5-chloro-1H-indole-2-carboxaMide|ingliforib

296

CP 296

CP 368296

CP296

CP-296

CP368296

CP-368296

INGLIFORIB; CP-296; CP-368; CP-368;296; CP296; CP 296; CP-368296; CP368296; CP 368296

CPD2802

Ingliforib

Ingliforib (CP 368296

GPi 296

5-chloro-N-((2S,3R)-4-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide

1H-Indole-2-carboxamide, 5-chloro-N-[(1S,2R)-3-[(3R,4S)-3,4-dihydroxy-1-pyrrolidinyl]-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-

Inhibitor,GPi296,GPi-296,CP368296,CP-368296,Ingliforib,inhibit

5-Chloro-N-((2S,3R)-4-((3R,4S)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-1H-indole-2-carboxamide

Ingliforib, 10 mM in DMSO

Ingliforib (CP 368296, GPi 296)

186392-65-4

peptides

APIs