(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

Product Name: (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
CAS No.: 196085-84-4
Chemical Name: (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
Synonyms: Atorvastatin Impurity Z;Atorvastatin Impurity 61;Atorvastatin calcium impurity 45;Atorvastatin A8 intermediate 4R6S Diastereomer;Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer;(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate;tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate;(4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester;1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-
CBNumber: CB62664118
Molecular Formula: C14H23NO4
Formula Weight: 269.34
MOL File: 196085-84-4.mol

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(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Property

Boiling point:: 364.1±17.0 °C(Predicted)
Density: 1.016±0.06 g/cm3(Predicted)
storage temp.: 2-8°C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C981895
Product name: (4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-aceticAcidtert-ButylEster
Packaging: 10mg
Price: $155
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0033545
Product name: TERT-BUTYL-2-((4R,6S)-6-(CYANOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE
Purity: 95.00%
Packaging: 5MG
Price: $503.73
Updated: 2021/12/16

Alichem

Product number: 196085844
Product name: tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
Packaging: 1g
Price: $2520
Updated: 2021/12/16

Crysdot

Product number: CD11171218
Product name: tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
Purity: 95+%
Packaging: 1g
Price: $2972
Updated: 2021/12/16

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(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Chemical Properties,Usage,Production

Uses

(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Suppliers

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196085-84-4, (4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetateRelated Search:

P-HYDROXY ATORVASTATIN LACTONE di(2-Hydroxy Atorvastatin) CalciuM Salt ATV-FX1 sodiuM salt Atorvastatin 3-Oxo Atorvastatin tert-Butyl Ester Atorvastatin Impurity 15 2,3-Dehydroxy Atorvastatin Sodium Salt Atorvastatin Impurity 20 Atorvastatin IMpurity G O-Methyl Atorvastatin Calcium Salt Ortho-Hydroxy atorvastatin calcium salt Atorvastatin Impurity 46 Atorvastatin Impurity 38 Atorvastatin Impurity 31 Difluoro Atorvastatin Acetonide tert-Butyl Ester 2-[1,2-Bis-(4-fluoro-phenyl)-2-oxo-ethyl]-4-methyl-3-oxo-pentanoic acid phenylamide Atorvastatin Dehydro Lactone 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate

Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer

Atorvastatin Impurity 61

Atorvastatin A8 intermediate 4R6S Diastereomer

Atorvastatin Impurity Z

(4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester

1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-

Atorvastatin calcium impurity 45

196085-84-4