5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride
- Product Name
- 5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride
- CAS No.
- 1338707-67-7
- Chemical Name
- 5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride
- Synonyms
- 5,6,7,8-TETRAHYDRO-1,7-NAPHTHYRIDINE HCL;5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride;1,7-Naphthyridine, 5,6,7,8-tetrahydro- (hydrochloride)
- CBNumber
- CB62665377
- Molecular Formula
- C8H11ClN2
- Formula Weight
- 170.63934
- MOL File
- 1338707-67-7.mol
5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride Property
- storage temp.
- Inert atmosphere,Room Temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T295973
- Product name
- 5,6,7,8-Tetrahydro-1,7-naphthyridinehydrochloride
- Packaging
- 25mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- T295973
- Product name
- 5,6,7,8-Tetrahydro-1,7-naphthyridinehydrochloride
- Packaging
- 5mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- Z4098
- Product name
- 5,6,7,8-Tetrahydro-1,7-naphthyridinehydrochloride
- Packaging
- 100mg
- Price
- $188
- Updated
- 2021/12/16
- Product number
- 35985
- Product name
- 5,6,7,8-Tetrahydro-1,7-naphthyridineHCl
- Purity
- 95+%
- Packaging
- 1g
- Price
- $1050
- Updated
- 2021/12/16
- Product number
- 1338707677
- Product name
- 5,6,7,8-Tetrahydro-1,7-naphthyridinehydrochloride
- Packaging
- 250mg
- Price
- $414.46
- Updated
- 2021/12/16
5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride Chemical Properties,Usage,Production
Uses
5,6,7,8-Tetrahydro-1,7-naphthyridine hydrochloride can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
5,6,7,8-Tetrahydro-[1,7]napthyridine hydrochloride. A methanolic solution (25 mL) of 7-Benzyl-5,6,7,8-tetrahydro-[1,7]naphthyridine (J. Het. Chem. 2001, 38, 535) (1.5g, 6.69 mmol) was degassed with argon for 20 min followed by the addition of 4N HCl in dioxane (2 mL) and Pd/C (300 mg, 20 wt%) and stirred under 50 psi hydrogen pressure at room temperature for 24h. After completion of the reaction the mixture was filtered on a short pad of celite and washed with methanol (4 × 25 mL). The filtrate was evaporated to dryness in vacuo and crystallized from methanol. Yield: 65% (calculated as 2HCl salt), 900 mg, yellowish solid.