3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

ChemicalBook > CAS DataBase List > 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

Product Name: 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
CAS No.: 890190-22-4
Chemical Name: 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester
Synonyms: WDR5-0103;WDR50103, >98%;WDR5(WDR5-0103);WD-Repeat Protein 5-0103;WD-REPEAT PROTEIN 5-0103;WDR5 0103;WDR50103;Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate;3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester;Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester
CBNumber: CB62695169
Molecular Formula: C21H25N3O4
Formula Weight: 383.44
MOL File: 890190-22-4.mol

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3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Property

Boiling point:: 495.2±45.0 °C(Predicted)
Density: 1.223±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
pka: 12.96±0.70(Predicted)
color: white to beige

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Safety

Hazard Codes: N
Risk Statements: 50/53
Safety Statements: 60-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 13945
Product name: WDR5-0103
Purity: ≥95%
Packaging: 1mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 13945
Product name: WDR5-0103
Purity: ≥95%
Packaging: 5mg
Price: $270
Updated: 2024/03/01

Cayman Chemical

Product number: 13945
Product name: WDR5-0103
Purity: ≥95%
Packaging: 10mg
Price: $477
Updated: 2024/03/01

Cayman Chemical

Product number: 13945
Product name: WDR5-0103
Purity: ≥95%
Packaging: 25mg
Price: $1041
Updated: 2024/03/01

Tocris

Product number: 5323
Product name: WDR50103
Purity: ≥99%(HPLC)
Packaging: 50
Price: $647
Updated: 2021/12/16

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3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Chemical Properties,Usage,Production

Description

WD-repeat protein 5 (WDR5) is a scaffold protein commonly involved in the formation of nucleosome-modifying protein complexes with histones. For example, WDR5 is a component of a mixed-lineage leukemia (MLL) methyltransferase complex that targets histone 3. WDR5 can also be a component of histone acetyltransferase complexes and can directly bind methylated as well as unmodified histones. WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (K_d = 450 nM), inhibiting the catalytic activity of the MLL core complex in vitro (IC₅₀ = 39 μM).

Uses

3-[(3-Methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)benzoic Acid Methyl Ester is an small molecule inhibitor of WDR5, an essential componet of the human trithorax-like famliy of SET1 methyltransferase complexes that carry out trimethylation of histone 3 Lys4.

storage

Store at +4°C

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester manufacturers

Career Henan Chemical Co

Product: 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester 890190-22-4
Price: US $0.10/g
Min. Order: 1g
Purity: 98%min
Supply Ability: 10g,100g
Release date: 2020-01-09

890190-22-4, 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl EsterRelated Search:

3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester

Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate

WDR5-0103

WDR50103, >98%

WD-Repeat Protein 5-0103

WD-REPEAT PROTEIN 5-0103;WDR5 0103;WDR50103

Benzoic acid, 3-[(3-methoxybenzoyl)amino]-4-(4-methyl-1-piperazinyl)-, methyl ester

WDR5(WDR5-0103)

890190-22-4

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