2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE Property

Melting point:

58-60 °C(lit.)

Boiling point:

224.0±40.0 °C(Predicted)

Density 

1.596±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

pka

3.30±0.33(Predicted)

BRN 

8319619

CAS DataBase Reference

86398-94-9(CAS DataBase Reference)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38-40

Safety Statements 

26-27-36/37/39-45

WGK Germany 

3

Hazard Note 

Irritant

HS Code 

29280000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

2,6-DICHLORO-4-(TRIFLUOROMETHYL)PHENYLHYDRAZINE Chemical Properties,Usage,Production

Uses

[2,6-Dichloro-4-(trifluoromethyl)phenyl]hydrazine may be used for the synthesis of pyrazolo[4,3-d]isoxazole derivatives. It may also be used in the synthesis of following N-(2,6-dichloro-4-trifluoromethyl)phenyl-N′-(1-phenylethylidene) hydrazines:

• N-(2,6-dichloro-4-trifluoromethyl)phenyl-N′-(1-phenylethylidene)hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-chlorophenyl)ethylidene]hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(3-chlorophenyl)ethylidene]hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-bromophenyl)-ethylidene]hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(3-bromophenyl)ethylidene]hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-methoxyphenyl)ethylidene]-hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-trifluoromethylphenyl)-ethylidene]hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(4-nitrophenyl)ethylidene]hydrazine
• N-(2,6-Dichloro-4-trifluoromethyl)phenyl-N′-[1-(6-methoxy-naphthalen-2-yl)-ethylidene]hydrazine

General Description

[2,6-Dichloro-4-(trifluoromethyl)phenyl]hydrazine is a hydrazine derivative. It reacts with excess of ethyl acetoacetate to afford 1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one.