7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one
- Product Name
- 7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one
- CAS No.
- 1154740-87-0
- Chemical Name
- 7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one
- Synonyms
- 7-Amino-6-methoxy-indan-1-one;7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one;1H-Inden-1-one, 7-amino-2,3-dihydro-6-methoxy-
- CBNumber
- CB62723390
- Molecular Formula
- C10H11NO2
- Formula Weight
- 177.2
- MOL File
- 1154740-87-0.mol
7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one Property
- Boiling point:
- 363.0±42.0 °C(Predicted)
- Density
- 1.254±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 2.37±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A898225
- Product name
- 7-Amino-6-methoxy-2,3-dihydro-1H-inden-1-one
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 5578DP
- Product name
- 7-Amino-6-methoxy-2,3-dihydro-1H-inden-1-one
- Packaging
- 5g
- Price
- $608
- Updated
- 2021/12/16
- Product number
- 127063
- Product name
- 7-Amino-6-methoxy-2,3-dihydro-1H-inden-1-one
- Purity
- >95%
- Packaging
- 1g
- Price
- $990
- Updated
- 2021/12/16
- Product number
- 61-11471
- Product name
- 7-Amino-6-methoxy-2,3-dihydro-1H-inden-1-one
- Purity
- 95-98%
- Packaging
- 5g
- Price
- $1240
- Updated
- 2021/12/16
- Product number
- CD12177894
- Product name
- 7-Amino-6-methoxy-2,3-dihydro-1H-inden-1-one
- Purity
- 97%
- Packaging
- 5g
- Price
- $1367
- Updated
- 2021/12/16
7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one Chemical Properties,Usage,Production
Synthesis
196597-96-3
1154740-87-0
Step i: 6-methoxy-7-nitro-1-indanone (10.0 g, 48.3 mmol) was dissolved in acetic acid (150 mL) at room temperature, followed by the addition of iron powder (10.8 g, 193 mmol). The reaction mixture was heated to 70 °C and stirred for 2 hours. After completion of the reaction, the mixture was cooled and filtered. The filtrate was concentrated under vacuum and the residue was diluted with ethyl acetate (300 mL) and washed sequentially with water (100 mL) and saturated saline (100 mL). The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated in vacuo to afford 7-amino-6-methoxy-2,3-dihydro-1H-inden-1-one (53b, 8.8 g, 100% yield) as a yellow solid. The product did not require further purification and could be used directly in the subsequent reaction.
References
[1] Patent: WO2009/62285, 2009, A1. Location in patent: Page/Page column 113
[2] Patent: WO2009/62285, 2009, A1. Location in patent: Page/Page column 76
[3] Patent: WO2009/62308, 2009, A1. Location in patent: Page/Page column 85-86
[4] Patent: WO2009/62288, 2009, A1. Location in patent: Page/Page column 82-83
[5] Patent: WO2009/62289, 2009, A1. Location in patent: Page/Page column 89-90
7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one Preparation Products And Raw materials
Raw materials
Preparation Products
7-AMino-6-Methoxy-2,3-dihydro-1H-inden-1-one Suppliers
- Tel
- 15026594951
- Fax
- 0556-5030632
- rs@raise-chem.com
- Country
- China
- ProdList
- 4454
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 400-685-9117
- Fax
- 021-51816740
- market@bepharm.com
- Country
- China
- ProdList
- 15081
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 13127280945
- 285424065@qq.com
- Country
- China
- ProdList
- 9976
- Advantage
- 55
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 13331045123
- Fax
- 86-10-80339217
- 2559355526@qq.com
- Country
- China
- ProdList
- 14193
- Advantage
- 58
- Tel
- 021-13482410-12 13482410112
- Fax
- -
- 362383684@qq.com
- Country
- China
- ProdList
- 737
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58