ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE
- Product Name
- ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE
- CAS No.
- 52119-38-7
- Chemical Name
- ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE
- Synonyms
- -3-oxopropanoate;Ethyl 3-(3-nitrophenyl);ETHYL 3-NITROBENZOYLACETATE;Ethyl 3-nitrobenzoylacetate 97%;ETHYL-2-(3-NITROBENZOYL)-ACETATE;3-Nitrobenzoylacetic acid ethyl ester;ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE;ethyl 3-(m-nitrophenyl)-3-oxopropionate;3-(3-nitrophenyl)-3-oxopropanoic acid ethyl ester;3-Oxo-3-(3-nitrophenyl)propionic acid ethyl ester
- CBNumber
- CB6272555
- Molecular Formula
- C11H11NO5
- Formula Weight
- 237.21
- MOL File
- 52119-38-7.mol
ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE Property
- Melting point:
- 75-77 °C (lit.)
- Boiling point:
- 314.4±17.0 °C(Predicted)
- Density
- 1.276±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder
- pka
- 9.52±0.46(Predicted)
- Appearance
- Light yellow to yellow Solid
- CAS DataBase Reference
- 52119-38-7(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 2918300090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 387444
- Product name
- Ethyl 3-nitrobenzoylacetate
- Purity
- 97%
- Packaging
- 25g
- Price
- $310
- Updated
- 2025/07/31
- Product number
- B124795
- Product name
- Ethyl 3-nitrobenzoylacetate
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- B124795
- Product name
- Ethyl 3-nitrobenzoylacetate
- Packaging
- 10g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 064484
- Product name
- Ethyl 3-(3-nitrophenyl)-3-oxopropanoate
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- O089
- Product name
- Ethyl3-(3-nitrophenyl)-3-oxopropanoate
- Packaging
- 5g
- Price
- $131
- Updated
- 2021/12/16
ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE Chemical Properties,Usage,Production
Uses
Ethyl (3-Nitrobenzoyl)acetate is used in the preparation of Dithiolethiones and identification of potential neuroprotective Agents
Synthesis
6148-64-7
121-90-4
52119-38-7
<2-l-1> Preparation of ethyl 3-(3-nitrophenyl)-3-oxopropionate: Monoethyl malonate potassium salt (21.4 g, 126 mmol) was suspended in acetonitrile (150 mL) at 0 °C. Triethylamine (18.3 mL, 132 mmol) and magnesium chloride (14.2 g, 149 mmol) were added sequentially, followed by stirring at room temperature under nitrogen protection for 150 min. M-nitrobenzoyl chloride (11.1 g, 59.8 mmol) was added slowly and stirring was continued at room temperature for 16 hours. After completion of the reaction, the solvent was removed by concentration under reduced pressure, the reaction was quenched by the addition of 1N HCl solution (100 mL) and extracted with ethyl acetate (100 mL x 2). The organic layers were combined, washed with water (100 mL) and dried over anhydrous magnesium sulfate. After filtration, the filtrate was concentrated under reduced pressure and purified by column chromatography (n-hexane/ethyl acetate, 4/1) to afford ethyl 3-nitrobenzoylacetate (14.1 g, 95%) as a light yellow solid.
References
[1] Patent: WO2008/69609, 2008, A1. Location in patent: Page/Page column 22-23
ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE Suppliers
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- Country
- France
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View Lastest Price from ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE manufacturers
- Product
- ETHYL 3-(3-NITROPHENYL)-3-OXOPROPANOATE 52119-38-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-20