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Aripiprazole Lauroxil

Product Name
Aripiprazole Lauroxil
CAS No.
1259305-29-7
Chemical Name
Aripiprazole Lauroxil
Synonyms
RDC 3317;1259305-29-7.;Aripiprazole Lauroxil;Pantoprazole Impurity 27 Hydrochloride;schizophrenia,Aristada,inhibit,Aripiprazole Lauroxil,Inhibitor;(7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl dodecanoate;Dodecanoic acid [7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2-oxo-1(2H)-quinolinyl]methyl ester
CBNumber
CB62738156
Molecular Formula
C36H51Cl2N3O4
Formula Weight
660.71
MOL File
1259305-29-7.mol
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Aripiprazole Lauroxil Property

Melting point:
83 - 84°C
Boiling point:
781.7±60.0 °C(Predicted)
Density 
1.153±0.06 g/cm3(Predicted)
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly, Sonicated)
form 
Solid
pka
7.67±0.10(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A771028
Product name
Aripiprazolelauroxil
Packaging
10mg
Price
$50
Updated
2021/12/16
DC Chemicals
Product number
012302
Product name
AripiprazoleLauroxil
Packaging
002
Price
$600
Updated
2021/12/16
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Aripiprazole Lauroxil Chemical Properties,Usage,Production

Description

Aripiprazole lauroxil is a long acting injectable (LAI) pro-drug formulation of aripiprazole approved in the U.S. for the treatment of schizophrenia. Aripiprazole lauroxil is a dopamine D2 receptor partial antagonist, a 5-HT2A antagonist, and a 5- HT1A partial agonist that was developed by Alkermes. It was Aripiprazole lauroxil is a long acting injectable (LAI) pro-drug formulation of aripiprazole approved in the U.S. for the treatment of schizophrenia.28 Aripiprazole lauroxil is a dopamine D2 receptor partial antagonist, a 5-HT2A antagonist, and a 5- HT1A partial agonist that was developed by Alkermes. It was

Definition

ChEBI: A dodecanoate ester obtained by formal condensation of the carboxy group of dodecanoic acid with the hydroxy group of 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-2-oxo-3,4-dihydroquinolin-1(2H)-yl]methanol. A prodrug for aripipraz le, it is used for treatment of schizophrenia.

Synthesis

The synthesis of aripiprazole lauroxil has only been described on gram scale in the patent literature. Commercially available aripiprazole (58) was treated with formaldehyde to give hemiaminal 59 in 65% crude yield and was then heated with lauric anhydride to give aripiprazole lauroxil (VII) in 21% overall yield.

Aripiprazole Lauroxil Preparation Products And Raw materials

Raw materials

Preparation Products

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Aripiprazole Lauroxil Suppliers

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View Lastest Price from Aripiprazole Lauroxil manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Aripiprazole Lauroxil 1259305-29-7
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000
Release date
2024-03-25
Shanghai Affida new material science and technology center
Product
Aripiprazole lauroxil 1259305-29-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99
Supply Ability
50000KG/month
Release date
2024-05-06
Shaanxi Dideu Medichem Co. Ltd
Product
Aripiprazole Lauroxil 1259305-29-7
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-25

1259305-29-7, Aripiprazole LauroxilRelated Search:

Dodecanamide Aripiprazole Lauroxil Intermediate

  • 1259305-29-7.
  • Aripiprazole Lauroxil
  • Dodecanoic acid [7-[4-[4-(2,3-dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2-oxo-1(2H)-quinolinyl]methyl ester
  • RDC 3317
  • schizophrenia,Aristada,inhibit,Aripiprazole Lauroxil,Inhibitor
  • Pantoprazole Impurity 27 Hydrochloride
  • (7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-2-oxo-3,4-dihydroquinolin-1(2H)-yl)methyl dodecanoate
  • 1259305-29-7
  • C36H51Cl2N3O4
  • API