2,5-Difluoro-4-iodoaniline

Product Name: 2,5-Difluoro-4-iodoaniline
CAS No.: 155906-13-1
Chemical Name: 2,5-Difluoro-4-iodoaniline
Synonyms: 2,5-Difluoro-4-iodoaniline;2,5-Difluoro-4-iodo-phenylamine;Benzenamine, 2,5-difluoro-4-iodo-
CBNumber: CB62743932
Molecular Formula: C6H4F2IN
Formula Weight: 255
MOL File: 155906-13-1.mol

More

Less

2,5-Difluoro-4-iodoaniline Property

storage temp.: 2-8°C(protect from light)
Appearance: Yellow to brown Solid

More

Less

Safety

HS Code: 2921420090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 1397AJ
Product name: 2,5-Difluoro-4-iodoaniline
Packaging: 1g
Price: $104
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-K-04
Product name: 2,5-Difluoro-4-iodoaniline
Purity: 96%
Packaging: 250mg
Price: $343
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0343971
Product name: 2,5-DIFLUORO-4-IODOANILINE
Purity: 95.00%
Packaging: 5MG
Price: $503.07
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3630-K-04
Product name: 2,5-Difluoro-4-iodoaniline
Purity: 96%
Packaging: 1g
Price: $655
Updated: 2021/12/16

J&W Pharmlab

Product number: 20R1241
Product name: 2,5-Difluoro-4-iodo-phenylamine
Purity: 96%
Packaging: 500mg
Price: $740
Updated: 2021/12/16

More

Less

2,5-Difluoro-4-iodoaniline Chemical Properties,Usage,Production

Synthesis

367-30-6

155906-13-1

General procedure for the synthesis of 2,5-difluoro-4-iodoaniline from 2,5-difluoroaniline: 2,5-difluoroaniline (0.5 g, 3.9 mmol), NaHCO3 (0.8 g, 9.8 mmol), I2 (2.5 g, 9.8 mmol), and H2O (50 mL) were mixed and stirred at room temperature. After 2 h of reaction, Na2SO3 (1 g, 8 mmol) was added, followed by extraction of the reaction mixture with CH2Cl2 (2 × 50 mL). The organic layers were combined, washed with H2O (50 mL), dried (MgSO4) and purified by fast chromatography through an Al2O3 column. The solvent was evaporated under vacuum to give the brown solid product 2,5-difluoro-4-iodoaniline (0.9 g, 91% yield). The 1H and 13C NMR spectra of the product were consistent with literature data. IR spectra (KBr, cm-1 ): 3464, 3379, 3042, 2926, 2855, 1632, 1501, 1414, 1323, 1298, 1234, 1184, 1167, 864, 837, 795, 733, 596, 444.1H NMR (500.13 MHz, CDCl3): δ= 7.27 (dd, 1H, JH3,F2=9.9, JH3,F5=5.6 Hz, H3), 6.52 (d, 1H, JH6,F5=8.7, JH6,F2=7.7 Hz, H6), 3.91 (br s, 2H, NH2).13C NMR (125.76 MHz, CDCl3): δ=158.0 (d 1JC5,F5=239.1 Hz, C5), 147.4 (d, 1JC2,F2=239.6 Hz, C2), 135.7 (dd, 2JC1,F2=14.7, 3JC1,F5=10.6 Hz, C1), 123.8 (dd, 2JC3,F2=22.8, 3JC3,F5=3.5 Hz, C3). 102.7 (dd, 2JC6,F5=29.9, 3JC6,F2=3.7 Hz, C6), 62.8 (dd, 2JC4,F5=29.1, 3JC4,F2=8.1 Hz, C4).19F NMR (282.37 MHz, CDCl3): δ=-101.5 (dd, 1F, JF5,F2=13.4 JF5,H6=8.7, JF5,H3=5.6 Hz, F5), -140.0 (ddd, 1F, JF2,F5=13.4, JF2,H3=9.9, JF2,H6=7.7 Hz, F2). High-resolution mass spectrum (EI): m/z calculated value 254.9351 [M]+, measured value 254.9356.

References

[1] Journal of Fluorine Chemistry, 2016, vol. 188, p. 85 - 98
[2] Canadian Journal of Chemistry, 2000, vol. 78, # 8, p. 1081 - 1088
[3] Patent: US5356558, 1994, A
[4] Synthesis (Germany), 2018, vol. 50, # 3, p. 555 - 564

2,5-Difluoro-4-iodoaniline Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2,5-Difluoro-4-iodoaniline Suppliers

China 38 India 1 United States 4 Global 43

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

BePharm Ltd

Tel: 400-685-9117
Fax: 021-51816740
Email: market@bepharm.com
Country: China
ProdList: 15081
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Zhengzhou Huiju Chemical Co., Ltd.

Tel: 0371-55900031 18137872243
Fax: QQ：2853979815
Email: 2853979815@qq.com
Country: China
ProdList: 9975
Advantage: 55

Dalian lichuang Chemical Co., Ltd

Tel: 0411-0411-00000000 13644282108
Fax: -
Email: 3500508746@qq.com
Country: China
ProdList: 2896
Advantage: 55

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Dandong Gilkuhn Import&Export Co., Ltd.

Tel: +86-519-83607890 18921087080
Fax: +86-519-83607890
Country: China
ProdList: 346
Advantage: 58

Suzhou Xiya Pharmaceutical Co., Ltd.

Tel: 0512-87819718 18912655635
Email: 2587879032@qq.com
Country: China
ProdList: 1401
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

155906-13-1, 2,5-Difluoro-4-iodoanilineRelated Search:

2,5-Difluoro-4-iodoaniline

2,5-Difluoro-4-iodo-phenylamine

Benzenamine, 2,5-difluoro-4-iodo-

155906-13-1