ChemicalBook > CAS DataBase List > N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide

Product Name
N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide
CAS No.
330829-30-6
Chemical Name
N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide
Synonyms
MRT-10;MRT-10 >=98% (HPLC);N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide;N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide;Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy-;N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide;ShhN signaling,inhibit,MRT10,MRT 10,cancer,Smoothened,Smo,Smo-induced IP accumulation,MRT-10,Bodipy-cyclopamine,SAG-induced AP activity,Inhibitor
CBNumber
CB62750479
Molecular Formula
C24H23N3O5S
Formula Weight
465.52
MOL File
330829-30-6.mol
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N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Property

storage temp. 
2-8°C
solubility 
DMSO: ≥15mg/mL
form 
powder
color 
white to tan
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Safety

Hazard Codes 
Xi,N
Risk Statements 
41-50
Safety Statements 
26-39-61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22138
Product name
MRT10
Purity
≥98%
Packaging
1mg
Price
$34
Updated
2024/03/01
Cayman Chemical
Product number
22138
Product name
MRT10
Purity
≥98%
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
22138
Product name
MRT10
Purity
≥98%
Packaging
10mg
Price
$166
Updated
2024/03/01
Cayman Chemical
Product number
22138
Product name
MRT10
Purity
≥98%
Packaging
25mg
Price
$371
Updated
2024/03/01
Tocris
Product number
4585
Product name
MRT10
Purity
≥98%
Packaging
50
Price
$680
Updated
2021/12/16
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N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Chemical Properties,Usage,Production

Description

MRT10 is an antagonist of the Smoothened (Smo) receptor with an IC50 value of 0.64 μM in a luciferase reporter assay. It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (IC50 = 0.5 μM) when expressed in HEK293 cells.

Uses

MRT 10, is a novel, high-affinity antagonist smoothened (Smo) receptor antagonist. It displaces labeled cyclopamine from Smo with an IC50 of 500 nM, and inhibits shh-induced Gli-reporter activity in Shh-light2 cells (IC50 = 0.64 μM).

N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide Suppliers

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330829-30-6, N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamideRelated Search:


  • MRT-10
  • N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide
  • N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide
  • Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy-
  • MRT-10 >=98% (HPLC)
  • N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide
  • ShhN signaling,inhibit,MRT10,MRT 10,cancer,Smoothened,Smo,Smo-induced IP accumulation,MRT-10,Bodipy-cyclopamine,SAG-induced AP activity,Inhibitor
  • 330829-30-6